Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 8/20 | 0.54 |
| ▸ | KLKB1 | P03952 | 15/20 | 0.48 |
| ▸ | KLK1 | P06870 | 6/20 | 0.48 |
| ▸ | F10 | P00742 | 2/20 | 0.48 |
| ▸ | PLG | P00747 | 1/20 | 0.48 |
| ▸ | F11 | P03951 | 1/20 | 0.48 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.48 |
| ▸ | CTRL | P40313 | 1/20 | 0.48 |
| ▸ | CTRB2 | Q6GPI1 | 1/20 | 0.48 |
| ▸ | CTRC | Q99895 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21748356 | 0.80 | F2 (0.69) | F2KLKB1KLK1F10PLG | |
| SCHEMBL19349041 | 0.78 | F2 (0.56) | F2KLKB1KLK1F10PLG | |
| SCHEMBL21748319 | 0.78 | F2 (0.70) | F2KLKB1KLK1F10PLG | |
| SCHEMBL19349094 | 0.77 | F2 (0.55) | F2KLKB1KLK1F10PLG | |
| SCHEMBL21748351 | 0.74 | F2 (0.58) | F2KLKB1KLK1F10PLG | |
| SCHEMBL21748344 | 0.74 | F2 (0.60) | F2KLKB1KLK1F10PLG | |
| SCHEMBL21748328 | 0.74 | F2 (0.60) | F2KLKB1KLK1F10PLG | |
| SCHEMBL21748364 | 0.73 | F2 (0.59) | F2KLKB1KLK1F10PLG | |
| SCHEMBL21748326 | 0.72 | F2 (0.61) | F2KLKB1KLK1F10PLG | |
| SCHEMBL17607887 | 0.72 | KLKB1 (0.43) | F2KLKB1KLK1F10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3194369-A1 | PYRAZOLYL-SUBSTITUTED PYRIDONE COMPOUNDS AS SERINE PROTEASE INHIBITORS | Verseon Corporation (US) | 2017-07-26 | — | — | EP | disclosed |
| WO-2016044662-A1 | PYRAZOLYL-SUBSTITUTED PYRIDONE COMPOUNDS AS SERINE PROTEASE INHIBITORS | VERSEON CORPORATION (US) | 2016-03-24 | — | — | WO | disclosed |