Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNC | P24863 | 11/20 | 0.72 |
| ▸ | CDK8 | P49336 | 11/20 | 0.72 |
| ▸ | HTR2A | P28223 | 1/20 | 0.72 |
| ▸ | PASK | Q96RG2 | 1/20 | 0.72 |
| ▸ | CDK19 | Q9BWU1 | 1/20 | 0.72 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.49 |
| ▸ | MAOB | P27338 | 3/20 | 0.42 |
| ▸ | MAOA | P21397 | 2/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | VNN1 | O95497 | 1/20 | 0.41 |
| ▸ | MPO | P05164 | 1/20 | 0.40 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.40 |
| ▸ | CDK7 | P50613 | 1/20 | 0.40 |
| ▸ | MLLT1 | Q03111 | 1/20 | 0.40 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17608642 | 0.93 | CCNC (0.71) | CCNCCDK8HTR2APASKCDK19 | |
| SCHEMBL17608343 | 0.90 | CCNC (0.57) | CCNCCDK8HTR2APASKCDK19 | |
| SCHEMBL17608431 | 0.89 | CCNC (0.56) | CCNCCDK8HTR2APASKCDK19 | |
| SCHEMBL17608763 | 0.89 | CCNC (0.58) | CCNCCDK8HTR2APASKCDK19 | |
| SCHEMBL17608438 | 0.86 | CCNC (0.66) | CCNCCDK8HTR2APASKCDK19 | |
| SCHEMBL31244861 | 0.84 | CCNC (1.00) | CCNCCDK8HTR2APASKCDK19 | |
| SCHEMBL17608164 | 0.83 | LRRK2 (0.51) | CCNCCDK8HTR2APASKCDK19 | |
| SCHEMBL17608768 | 0.83 | CCNC (0.75) | CCNCCDK8HTR2APASKCDK19 | |
| SCHEMBL17608569 | 0.83 | CCNC (0.57) | CCNCCDK8HTR2APASKCDK19 | |
| SCHEMBL17608608 | 0.82 | CDK8 (0.57) | CCNCCDK8HTR2APASKCDK19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016041618-A1 | SUBSTITUTED INDAZOLES AND RELATED HETEROCYCLES | MERCK PATENT GMBH (DE) | 2016-03-24 | — | — | WO | claimed |
| US-20200123499-A1 | METHOD FOR EFFICIENT GENERATION OF NEURONS FROM NON-NEURONAL CELLS | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2020-04-23 | — | — | US | disclosed |
| WO-2016041618-A1 | SUBSTITUTED INDAZOLES AND RELATED HETEROCYCLES | MERCK PATENT GMBH (DE) | 2016-03-24 | — | — | WO | disclosed |