SCHEMBL17609289

SCHEMBL17609289

COCC(C)(C)c1ccc(N(C)c2ccc(Oc3ncc4ccncc4n3)cc2)cc1

nearest known ligand 0.60

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
KDM4C Q9H3R0 20/20 0.60

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17602256 0.84 KDM4C (0.57) KDM4C
SCHEMBL17602260 0.83 KDM4C (0.65) KDM4C
SCHEMBL17602095 0.82 KDM4C (0.53) KDM4C
SCHEMBL17609163 0.81 KDM4C (0.54) KDM4C
SCHEMBL30139680 0.81 KDM4C (0.54) KDM4C
SCHEMBL17609143 0.81 KDM4C (0.54) KDM4C
SCHEMBL17609371 0.79 KDM4C (0.57) KDM4C
SCHEMBL17602163 0.78 KDM4C (0.58) KDM4C
SCHEMBL17609134 0.77 KDM4C (0.57) KDM4C
SCHEMBL30342471 0.77 KDM4C (0.57) KDM4C

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3193601-A1 HISTONE DEMETHYLASE INHIBITORS Celgene Quanticel Research, Inc. (US) 2017-07-26 EP claimed
WO-2016044429-A1 HISTONE DEMETHYLASE INHIBITORS Quanticel Pharmaceuticals, Inc. (US) 2016-03-24 WO claimed