Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 13/20 | 0.85 |
| ▸ | SMN1; SMN2 | Q16637 | 9/20 | 0.85 |
| ▸ | MAPT | P10636 | 4/20 | 0.85 |
| ▸ | LMNA | P02545 | 3/20 | 0.85 |
| ▸ | TP53 | P04637 | 3/20 | 0.85 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.85 |
| ▸ | MIF | P14174 | 1/20 | 0.76 |
| ▸ | USP2 | O75604 | 10/20 | 0.65 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.65 |
| ▸ | MEN1 | O00255 | 1/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.65 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.61 |
| ▸ | SLCO1B3 | Q9NPD5 | 3/20 | 0.60 |
| ▸ | SLCO1B1 | Q9Y6L6 | 3/20 | 0.60 |
| ▸ | APEX1 | P27695 | 1/20 | 0.60 |
| ▸ | GLA | P06280 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15604116 | 1.00 | CYP3A4 (0.85) | CYP3A4SMN1; SMN2MAPTLMNATP53 | |
| SCHEMBL16727974 | 1.00 | CYP3A4 (0.85) | CYP3A4SMN1; SMN2MAPTLMNATP53 | |
| Gedunin SCHEMBL598969 | 0.92 | CYP3A4 (1.00) | CYP3A4SMN1; SMN2MAPTLMNATP53 | |
| Gedunin SCHEMBL12664640 | 0.92 | CYP3A4 (1.00) | CYP3A4SMN1; SMN2MAPTLMNATP53 | |
| Gedunin SCHEMBL16731398 | 0.92 | CYP3A4 (1.00) | CYP3A4SMN1; SMN2MAPTLMNATP53 | |
| Gedunin SCHEMBL23134885 | 0.92 | CYP3A4 (1.00) | CYP3A4SMN1; SMN2MAPTLMNATP53 | |
| Gedunin SCHEMBL14197009 | 0.92 | CYP3A4 (1.00) | CYP3A4SMN1; SMN2MAPTLMNATP53 | |
| Gedunin SCHEMBL10019479 | 0.92 | CYP3A4 (1.00) | CYP3A4SMN1; SMN2MAPTLMNATP53 | |
| Gedunin SCHEMBL12998444 | 0.92 | CYP3A4 (1.00) | CYP3A4SMN1; SMN2MAPTLMNATP53 | |
| Gedunin SCHEMBL17603575 | 0.92 | CYP3A4 (1.00) | CYP3A4SMN1; SMN2MAPTLMNATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9289412-B2 | Role of limonoid compounds as neuroprotective agents | THE JOHNS HOPKINS UNIVERSITY (US) | 2016-03-22 | — | — | US | disclosed |