SCHEMBL17612751

SCHEMBL17612751

O=C(O)c1ccc(N2CC3(CCN(Cc4cn(C5CC5)nc4-c4ccc(O)cc4)CC3)OC2=O)cc1

nearest known ligand 0.83

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
SSTR5 P35346 20/20 0.83

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10284096 0.96 SSTR5 (0.84) SSTR5
SCHEMBL10283913 0.91 SSTR5 (1.00) SSTR5
SCHEMBL10284069 0.87 SSTR5 (1.00) SSTR5
SCHEMBL672128 0.85 SSTR5 (1.00) SSTR5
SCHEMBL14958063 0.84 SSTR5 (1.00) SSTR5
SCHEMBL671658 0.82 SSTR5 (1.00) SSTR5
SCHEMBL14957125 0.82 SSTR5 (1.00) SSTR5
SCHEMBL17612804 0.81 SSTR5 (0.89) SSTR5
SCHEMBL673072 0.81 SSTR5 (1.00) SSTR5
SCHEMBL14957007 0.81 SSTR5 (1.00) SSTR5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2605658-B1 SPIROXAZOLIDINONE COMPOUNDS MERCK SHARP & DOHME (US) 2016-03-23 EP disclosed