SCHEMBL17612784

SCHEMBL17612784

O=C(O)c1ccc(N2CC3(CCN(Cc4cc(C5CC5)c(CI)cc4Cl)CC3)OC2=O)cc1

nearest known ligand 0.72

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ SSTR5 P35346 20/20 0.72

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17612772 0.92 SSTR5 (0.68) SSTR5
SCHEMBL670645 0.91 SSTR5 (0.73) SSTR5
SCHEMBL10284052 0.89 SSTR5 (0.70) SSTR5
SCHEMBL671591 0.88 SSTR5 (0.76) SSTR5
SCHEMBL10284079 0.85 SSTR5 (0.70) SSTR5
SCHEMBL14957449 0.84 SSTR5 (1.00) SSTR5
SCHEMBL671204 0.83 SSTR5 (0.77) SSTR5
SCHEMBL669379 0.83 SSTR5 (0.74) SSTR5
SCHEMBL671267 0.82 SSTR5 (0.74) SSTR5
SCHEMBL17612781 0.82 SSTR5 (0.62) SSTR5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2605658-B1 SPIROXAZOLIDINONE COMPOUNDS MERCK SHARP & DOHME (US) 2016-03-23 — — EP disclosed
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