Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 14/20 | 0.52 |
| ▸ | BCR | P11274 | 14/20 | 0.52 |
| ▸ | BRAF | P15056 | 5/20 | 0.52 |
| ▸ | TEK | Q02763 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12465173 | 0.90 | BRAF (0.52) | ABL1BCRBRAFTEK | |
| SCHEMBL12465136 | 0.89 | TEK (0.62) | ABL1BCRBRAFTEK | |
| SCHEMBL12465331 | 0.88 | ABL1 (0.55) | ABL1BCRBRAFTEK | |
| SCHEMBL12465134 | 0.87 | BRAF (0.49) | ABL1BCRBRAF | |
| SCHEMBL12465324 | 0.81 | ABL1 (0.46) | ABL1BCRBRAF | |
| SCHEMBL12397175 | 0.80 | BRAF (0.57) | ABL1BCRBRAF | |
| SCHEMBL12465338 | 0.79 | TEK (0.58) | ABL1BCRBRAFTEK | |
| SCHEMBL12465129 | 0.78 | ABL1 (0.53) | ABL1BCRBRAFTEK | |
| SCHEMBL12465012 | 0.78 | BRAF (0.49) | ABL1BCRBRAF | |
| SCHEMBL13960367 | 0.77 | BRAF (0.59) | ABL1BCRBRAF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2173734-B1 | CHEMICAL COMPOUNDS | BOEHRINGER INGELHEIM INT (DE) | 2016-03-23 | — | — | EP | disclosed |