Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 5/20 | 0.50 |
| ▸ | BCR | P11274 | 5/20 | 0.50 |
| ▸ | BRAF | P15056 | 14/20 | 0.49 |
| ▸ | GPR142 | Q7Z601 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12398168 | 1.00 | ABL1 (0.50) | ABL1BCRBRAFGPR142 | |
| SCHEMBL12398073 | 0.93 | ABL1 (0.51) | ABL1BCRBRAFGPR142 | |
| SCHEMBL12398018 | 0.91 | BRAF (0.60) | ABL1BCRBRAFGPR142 | |
| SCHEMBL12398091 | 0.91 | BRAF (0.60) | ABL1BCRBRAFGPR142 | |
| SCHEMBL12398094 | 0.91 | BRAF (0.60) | ABL1BCRBRAFGPR142 | |
| SCHEMBL12398079 | 0.91 | ABL1 (0.52) | ABL1BCRBRAFGPR142 | |
| SCHEMBL17612911 | 0.90 | ABL1 (0.51) | ABL1BCRBRAFGPR142 | |
| SCHEMBL12398053 | 0.90 | BRAF (0.59) | ABL1BCRBRAFGPR142 | |
| SCHEMBL12398051 | 0.90 | BRAF (0.51) | ABL1BCRBRAFGPR142 | |
| SCHEMBL12397996 | 0.90 | BRAF (0.56) | ABL1BCRBRAFGPR142 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2173734-B1 | CHEMICAL COMPOUNDS | BOEHRINGER INGELHEIM INT (DE) | 2016-03-23 | — | — | EP | disclosed |