Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.37 |
| ▸ | BHMT | Q93088 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13425137 | 0.86 | — | — | |
| SCHEMBL6624332 | 0.76 | SMN1; SMN2 (0.39) | — | |
| SCHEMBL13853422 | 0.72 | — | — | |
| SCHEMBL17613656 | 0.71 | TDP1 (0.46) | TDP1ROCK2 | |
| SCHEMBL12023026 | 0.71 | TSHR (0.40) | — | |
| SCHEMBL6548989 | 0.70 | — | — | |
| Thiodiglycol SCHEMBL27559563 | 0.70 | TP53 (0.55) | TDP1ROCK2BHMT | |
| SCHEMBL17613605 | 0.70 | TDP1 (0.43) | TDP1 | |
| SCHEMBL195715 | 0.69 | TDP1 (0.91) | TDP1ROCK2 | |
| SCHEMBL9638413 | 0.69 | TDP1 (0.91) | TDP1ROCK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2346883-B1 | SELF DELIVERING BIO-LABILE PHOSPHATE PROTECTED PRO-OLIGOS FOR OLIGONUCLEOTIDE BASED THERAPEUTICS AND MEDIATING RNA INTERFERENCE | PETERSEN SCOTT G (US) | 2016-03-23 | — | — | EP | disclosed |