Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 2/20 | 0.37 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17613695 | 0.88 | TSHR (0.36) | TSHR | |
| SCHEMBL17613697 | 0.85 | TSHR (0.39) | SMN1; SMN2TSHR | |
| SCHEMBL10923335 | 0.81 | — | — | |
| SCHEMBL17613646 | 0.76 | TSHR (0.37) | CYP4F2CYP4A11KDM4ESMN1; SMN2TSHR | |
| SCHEMBL17613651 | 0.74 | — | — | |
| SCHEMBL17613662 | 0.73 | CYP4F2 (0.30) | CYP4F2CYP4A11 | |
| SCHEMBL17613640 | 0.73 | KDM4E (0.31) | CYP4F2CYP4A11KDM4ESMN1; SMN2TSHR | |
| SCHEMBL15833401 | 0.73 | KDM4E (0.35) | CYP4F2CYP4A11KDM4ESMN1; SMN2TDP1 | |
| SCHEMBL12198870 | 0.71 | SMN1; SMN2 (0.39) | CYP4F2CYP4A11KDM4ESMN1; SMN2TDP1 | |
| SCHEMBL2171182 | 0.71 | TSHR (0.40) | CYP4F2CYP4A11TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2346883-B1 | SELF DELIVERING BIO-LABILE PHOSPHATE PROTECTED PRO-OLIGOS FOR OLIGONUCLEOTIDE BASED THERAPEUTICS AND MEDIATING RNA INTERFERENCE | PETERSEN SCOTT G (US) | 2016-03-23 | — | — | EP | disclosed |