Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.44 |
| ▸ | TTR | P02766 | 1/20 | 0.36 |
| ▸ | DPP4 | P27487 | 1/20 | 0.36 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | CNR1 | P21554 | 2/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA7 | P43166 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.36 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.36 |
| ▸ | PGR | P06401 | 1/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16852848 | 0.89 | MAPT (0.56) | MAPTALDH1A1HCAR2TTRDPP4 | |
| SCHEMBL28532594 | 0.89 | MAPT (0.56) | MAPTALDH1A1HCAR2TTRDPP4 | |
| SCHEMBL12966124 | 0.89 | MAPT (0.49) | MAPTALDH1A1HCAR2ZDHHC20ATM | |
| SCHEMBL22100454 | 0.83 | MAPT (0.85) | MAPTALDH1A1HCAR2TTRDPP4 | |
| SCHEMBL2618106 | 0.80 | MAPT (0.72) | MAPTALDH1A1HCAR2TTRDPP4 | |
| SCHEMBL1885350 | 0.80 | MAPT (0.72) | MAPTALDH1A1HCAR2TTRDPP4 | |
| SCHEMBL872986 | 0.78 | MAPT (0.70) | MAPTALDH1A1HCAR2ATMNPSR1 | |
| SCHEMBL29131601 | 0.78 | MAPT (0.70) | MAPTALDH1A1HCAR2TTRDPP4 | |
| SCHEMBL872985 | 0.78 | MAPT (0.70) | MAPTALDH1A1HCAR2ATMNPSR1 | |
| SCHEMBL27487508 | 0.78 | MAPT (0.70) | MAPTALDH1A1HCAR2ATMNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170192012-A1 | COMPOSITIONS AND METHODS FOR DETECTING S-NITROSYLATION AND S-SULFINYLATION | THE REGENTS OF THE UNIVERSITY OF MICHIGAN | 2017-07-06 | — | — | US | disclosed |
| US-20160084845-A1 | COMPOSITIONS AND METHODS FOR DETECTING S-NITROSYLATION AND S-SULFINYLATION | THE REGENTS OF THE UNIVERSITY OF MICHIGAN | 2016-03-24 | — | — | US | disclosed |