Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE2 | Q9BYF1 | 2/20 | 0.83 |
| ▸ | ADORA3 | P0DMS8 | 5/20 | 0.64 |
| ▸ | POLH | Q9Y253 | 2/20 | 0.64 |
| ▸ | ABCG2 | Q9UNQ0 | 3/20 | 0.56 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.56 |
| ▸ | ABCC1 | P33527 | 2/20 | 0.56 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17620379 | 0.94 | ACE2 (0.94) | ACE2ADORA3POLHABCG2ABCB1 | |
| SCHEMBL17620268 | 0.92 | ACE2 (0.80) | ACE2POLHABCG2ABCB1ABCC1 | |
| SCHEMBL17620266 | 0.91 | ACE2 (0.77) | ACE2ADORA3POLHABCG2ABCB1 | |
| SCHEMBL8737505 | 0.90 | ACE2 (0.79) | ACE2ADORA3POLHABCG2ABCB1 | |
| SCHEMBL12866149 | 0.89 | ACE2 (0.78) | ACE2ADORA3POLHABCG2ABCB1 | |
| SCHEMBL13941669 | 0.89 | ACE2 (0.78) | ACE2ADORA3POLHABCG2ABCB1 | |
| SCHEMBL13076849 | 0.89 | ACE2 (0.78) | ACE2ADORA3POLHABCG2ABCB1 | |
| SCHEMBL15918780 | 0.89 | ACE2 (0.74) | ACE2POLHABCB1 | |
| SCHEMBL13081655 | 0.88 | ACE2 (0.74) | ACE2ADORA3POLHABCG2ABCB1 | |
| SCHEMBL12866476 | 0.88 | ACE2 (0.76) | ACE2ADORA3POLHABCG2ABCB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016041195-A1 | FLAVONE GLYCOSIDE DERIVATIVES AND PREPARATION METHOD AND USE THEREOF | 贵州百灵企业集团制药股份有限公司 | 2016-03-24 | — | — | WO | disclosed |