Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17620332 | 1.00 | BACE1 (0.51) | BACE1CTSD | |
| SCHEMBL8754 | 1.00 | BACE1 (0.51) | BACE1CTSD | |
| SCHEMBL8654 | 0.92 | BACE1 (0.52) | BACE1CTSD | |
| SCHEMBL11168 | 0.90 | BACE1 (0.54) | BACE1CTSD | |
| SCHEMBL11077 | 0.89 | BACE1 (0.68) | BACE1CTSD | |
| SCHEMBL9408 | 0.86 | BACE1 (0.59) | BACE1CTSD | |
| SCHEMBL9071 | 0.83 | BACE1 (0.72) | BACE1CTSD | |
| SCHEMBL1767940 | 0.79 | BACE1 (0.42) | BACE1CTSD | |
| SCHEMBL2228735 | 0.79 | GBA1 (0.42) | — | |
| SCHEMBL2226685 | 0.78 | GBA1 (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9296698-B2 | Amino heteroaryl compounds as beta-secretase modulators and methods of use | AMGEN INC. (US) | 2016-03-29 | — | — | US | claimed |