Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17620347 | 1.00 | BACE1 (0.65) | BACE1CTSD | |
| SCHEMBL17620326 | 1.00 | BACE1 (0.65) | BACE1CTSD | |
| SCHEMBL17620297 | 0.83 | BACE1 (0.70) | BACE1CTSD | |
| SCHEMBL8498 | 0.80 | BACE1 (0.78) | BACE1CTSD | |
| SCHEMBL8994 | 0.79 | BACE1 (1.00) | BACE1CTSD | |
| SCHEMBL14321762 | 0.79 | BACE1 (1.00) | BACE1CTSD | |
| SCHEMBL17620352 | 0.79 | BACE1 (0.87) | BACE1CTSD | |
| SCHEMBL14321154 | 0.79 | BACE1 (0.65) | BACE1CTSD | |
| SCHEMBL11539 | 0.79 | BACE1 (0.65) | BACE1CTSD | |
| SCHEMBL11458 | 0.79 | BACE1 (0.65) | BACE1CTSD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9296698-B2 | Amino heteroaryl compounds as beta-secretase modulators and methods of use | AMGEN INC. (US) | 2016-03-29 | — | — | US | claimed |