Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PHF8 | Q9UPP1 | 7/20 | 0.63 |
| ▸ | KDM4C | Q9H3R0 | 9/20 | 0.63 |
| ▸ | KDM4A | O75164 | 4/20 | 0.63 |
| ▸ | KDM2B | Q8NHM5 | 2/20 | 0.56 |
| ▸ | KDM5A | P29375 | 7/20 | 0.55 |
| ▸ | KDM5B | Q9UGL1 | 7/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16034010 | 0.90 | KDM4C (0.68) | PHF8KDM4CKDM4AKDM2BKDM5A | |
| SCHEMBL20978964 | 0.85 | PHF8 (0.58) | PHF8KDM4CKDM4AKDM2BKDM5A | |
| SCHEMBL19383516 | 0.82 | KDM2B (0.55) | PHF8KDM4CKDM4AKDM2BKDM5A | |
| SCHEMBL16034376 | 0.79 | PHF8 (0.62) | PHF8KDM4CKDM4AKDM2BKDM5A | |
| SCHEMBL16035020 | 0.77 | KDM4C (1.00) | PHF8KDM4CKDM4AKDM2BKDM5A | |
| SCHEMBL16034818 | 0.77 | KDM4C (1.00) | PHF8KDM4CKDM4AKDM2BKDM5A | |
| SCHEMBL29376754 | 0.76 | KDM4C (0.73) | PHF8KDM4CKDM4AKDM2BKDM5A | |
| SCHEMBL17604514 | 0.76 | KDM4C (0.73) | PHF8KDM4CKDM4AKDM2BKDM5A | |
| SCHEMBL17693182 | 0.74 | KDM4C (0.70) | PHF8KDM4CKDM4AKDM2BKDM5A | |
| SCHEMBL17898969 | 0.73 | KDM4C (0.69) | PHF8KDM4CKDM4AKDM2BKDM5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016044342-A1 | HISTONE DEMETHYLASE INHIBITORS | Quanticel Pharmaceuticals, Inc. (US) | 2016-03-24 | — | — | WO | disclosed |