Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4C | Q9H3R0 | 6/20 | 0.56 |
| ▸ | KDM2B | Q8NHM5 | 4/20 | 0.56 |
| ▸ | KDM5A | P29375 | 2/20 | 0.56 |
| ▸ | PHF8 | Q9UPP1 | 7/20 | 0.52 |
| ▸ | KDM5B | Q9UGL1 | 4/20 | 0.50 |
| ▸ | KDM6B | O15054 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30589239 | 0.90 | KDM4C (0.63) | KDM4CKDM2BKDM5APHF8KDM5B | |
| SCHEMBL17891734 | 0.90 | KDM4C (0.63) | KDM4CKDM2BKDM5APHF8KDM5B | |
| SCHEMBL17891762 | 0.90 | KDM2B (0.57) | KDM4CKDM2BKDM5APHF8KDM5B | |
| SCHEMBL17695516 | 0.90 | KDM4C (0.69) | KDM4CKDM2BKDM5APHF8KDM5B | |
| SCHEMBL17695473 | 0.89 | PHF8 (0.67) | KDM4CKDM2BKDM5APHF8KDM5B | |
| SCHEMBL24244162 | 0.89 | KDM5B (0.57) | KDM4CKDM2BKDM5APHF8KDM5B | |
| SCHEMBL17621557 | 0.87 | KDM2B (0.72) | KDM4CKDM2BKDM5APHF8KDM5B | |
| SCHEMBL17695474 | 0.86 | PHF8 (0.66) | KDM4CKDM2BKDM5APHF8KDM5B | |
| SCHEMBL30589222 | 0.86 | KDM5B (0.56) | KDM4CKDM2BKDM5APHF8KDM5B | |
| SCHEMBL17891752 | 0.86 | KDM5B (0.56) | KDM4CKDM2BKDM5APHF8KDM5B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016044342-A1 | HISTONE DEMETHYLASE INHIBITORS | Quanticel Pharmaceuticals, Inc. (US) | 2016-03-24 | — | — | WO | disclosed |