Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM5B | Q9UGL1 | 14/20 | 0.57 |
| ▸ | KDM2B | Q8NHM5 | 4/20 | 0.57 |
| ▸ | KDM4C | Q9H3R0 | 5/20 | 0.51 |
| ▸ | KDM5A | P29375 | 3/20 | 0.51 |
| ▸ | KDM4A | O75164 | 1/20 | 0.42 |
| ▸ | KDM6B | O15054 | 1/20 | 0.40 |
| ▸ | PHF8 | Q9UPP1 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17695512 | 0.92 | KDM5B (0.58) | KDM5BKDM2BKDM4CKDM5AKDM4A | |
| SCHEMBL17695519 | 0.91 | KDM5B (0.57) | KDM5BKDM2BKDM4CKDM5AKDM4A | |
| SCHEMBL17621784 | 0.91 | KDM5B (0.69) | KDM5BKDM2BKDM4CKDM5AKDM4A | |
| SCHEMBL17621697 | 0.88 | KDM5B (0.54) | KDM5BKDM2BKDM4CKDM5AKDM4A | |
| SCHEMBL17621781 | 0.85 | KDM5B (0.57) | KDM5BKDM2BKDM4CKDM5AKDM4A | |
| SCHEMBL17621693 | 0.85 | KDM5B (0.56) | KDM5BKDM2BKDM4CKDM5AKDM4A | |
| SCHEMBL17621780 | 0.83 | KDM5B (0.54) | KDM5BKDM2BKDM4CKDM5AKDM4A | |
| SCHEMBL17621698 | 0.82 | KDM5B (0.53) | KDM5BKDM2BKDM4CKDM5AKDM4A | |
| SCHEMBL17891709 | 0.81 | KDM5B (0.68) | KDM5BKDM2BKDM4CKDM5AKDM4A | |
| SCHEMBL17693166 | 0.79 | KDM5B (0.54) | KDM5BKDM2BKDM4CKDM5AKDM4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016044342-A1 | HISTONE DEMETHYLASE INHIBITORS | Quanticel Pharmaceuticals, Inc. (US) | 2016-03-24 | — | — | WO | disclosed |