Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 2/20 | 0.47 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | TYMS | P04818 | 1/20 | 0.39 |
| ▸ | BRD1 | O95696 | 5/20 | 0.37 |
| ▸ | BRPF1 | P55201 | 5/20 | 0.37 |
| ▸ | BRD4 | O60885 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | TAF1 | P21675 | 4/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | CASP1 | P29466 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.36 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17622190 | 0.90 | ESR1 (0.44) | ESR1ESR2MEN1KMT2ABRD1 | |
| SCHEMBL17622222 | 0.87 | TP53 (0.45) | ESR1ESR2TP53HPGDMEN1 | |
| SCHEMBL17622169 | 0.85 | ANPEP (0.45) | ESR1MEN1KMT2AALDH1A1NPC1 | |
| SCHEMBL17622179 | 0.84 | POLB (0.46) | ESR1ESR2MEN1KMT2AALDH1A1 | |
| SCHEMBL17622349 | 0.83 | CA9 (0.44) | ESR1ESR2TP53HPGDMEN1 | |
| SCHEMBL19431022 | 0.83 | TP53 (0.38) | ESR1ESR2TP53HPGDMEN1 | |
| SCHEMBL17622168 | 0.83 | ESR1 (0.46) | ESR1ESR2MEN1KMT2ABRD4 | |
| SCHEMBL17622187 | 0.82 | MEN1 (0.55) | ESR1ESR2MEN1KMT2AALDH1A1 | |
| SCHEMBL17622184 | 0.81 | ESR1 (0.50) | ESR1ESR2MEN1KMT2ABRD4 | |
| SCHEMBL19421871 | 0.80 | TP53 (0.46) | ESR1ESR2TP53HPGDMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10651394-B2 | Organic molecules for use as emitters | CYNORA GMBH (DE) | 2020-05-12 | — | — | US | disclosed |
| EP-3246373-A1 | ORGANIC MOLECULES FOR USE AS EMITTERS | cynora GmbH (DE) | 2017-11-22 | — | — | EP | disclosed |
| US-20170288149-A1 | ORGANIC MOLECULES FOR USE AS EMITTERS | CYNORA GMBH (DE) | 2017-10-05 | — | — | US | disclosed |
| US-20170288149-A1 | ORGANIC MOLECULES FOR USE AS EMITTERS | CYNORA GMBH (DE) | 2017-10-05 | — | — | US | disclosed |
| WO-2016042070-A1 | ORGANIC MOLECULES FOR USE AS EMITTERS | CYNORA GMBH (DE) | 2016-03-24 | — | — | WO | disclosed |