Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC5A2 | P31639 | 19/20 | 0.76 |
| ▸ | SLC5A1 | P13866 | 10/20 | 0.76 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.76 |
| ▸ | SLC5A11 | Q8WWX8 | 1/20 | 0.76 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15906633 | 0.91 | SLC5A2 (0.63) | SLC5A2SLC5A1ADRA2ASLC5A11 | |
| SCHEMBL18265028 | 0.91 | SLC5A2 (0.63) | SLC5A2SLC5A1ADRA2ASLC5A11 | |
| SCHEMBL17189397 | 0.90 | SLC5A2 (0.62) | SLC5A2SLC5A1ADRA2ASLC5A11 | |
| SCHEMBL18265012 | 0.90 | SLC5A2 (0.72) | SLC5A2SLC5A1ADRA2ASLC5A11 | |
| SCHEMBL27413751 | 0.89 | SLC5A2 (0.61) | SLC5A2SLC5A1ADRA2ASLC5A11 | |
| SCHEMBL19867561 | 0.89 | SLC5A2 (0.81) | SLC5A2SLC5A1ADRA2ASLC5A11 | |
| SCHEMBL18265051 | 0.87 | SLC5A2 (0.86) | SLC5A2SLC5A1ADRA2ASLC5A11 | |
| SCHEMBL12285731 | 0.87 | SLC5A2 (0.86) | SLC5A2SLC5A1ADRA2ASLC5A11 | |
| SCHEMBL12108733 | 0.87 | SLC5A2 (0.86) | SLC5A2SLC5A1ADRA2ASLC5A11 | |
| SCHEMBL2383465 | 0.86 | SLC5A2 (0.72) | SLC5A2SLC5A1ADRA2ASLC5A11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016041470-A1 | SGLT-2 INHIBITORS | NATIONAL INSTITUTE OF BIOLOGICAL SCIENCES, BEIJING (CN) | 2016-03-24 | — | — | WO | disclosed |