Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4C | Q9H3R0 | 19/20 | 0.66 |
| ▸ | KDM5A | P29375 | 2/20 | 0.35 |
| ▸ | KDM5B | Q9UGL1 | 2/20 | 0.35 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.34 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.34 |
| ▸ | KDM6B | O15054 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29542558 | 0.97 | KDM4C (0.69) | KDM4CKDM5AKDM5BCYP19A1TBXAS1 | |
| SCHEMBL17602194 | 0.97 | KDM4C (0.69) | KDM4CKDM5AKDM5BCYP19A1TBXAS1 | |
| SCHEMBL17602132 | 0.94 | KDM4C (0.68) | KDM4C | |
| SCHEMBL29542181 | 0.94 | KDM4C (0.68) | KDM4C | |
| SCHEMBL17615753 | 0.83 | KDM4C (0.51) | KDM4CKDM6B | |
| SCHEMBL17898300 | 0.83 | KDM4C (0.45) | KDM4C | |
| SCHEMBL17898296 | 0.82 | KDM4C (0.44) | KDM4C | |
| SCHEMBL17615747 | 0.81 | KDM4C (0.46) | KDM4CKDM5AKDM5B | |
| SCHEMBL17898302 | 0.78 | KDM4C (0.44) | KDM4C | |
| SCHEMBL17602134 | 0.78 | KDM4C (0.44) | KDM4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016044429-A1 | HISTONE DEMETHYLASE INHIBITORS | Quanticel Pharmaceuticals, Inc. (US) | 2016-03-24 | — | — | WO | disclosed |