Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYR | P14679 | 1/20 | 0.75 |
| ▸ | SLC5A1 | P13866 | 1/20 | 0.67 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.67 |
| ▸ | NPC1 | O15118 | 2/20 | 0.62 |
| ▸ | RAB9A | P51151 | 2/20 | 0.62 |
| ▸ | IL2 | P60568 | 1/20 | 0.60 |
| ▸ | POLB | P06746 | 1/20 | 0.59 |
| ▸ | ACHE | P22303 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7945567 | 1.00 | TYR (0.75) | TYRSLC5A1SLC5A2NPC1RAB9A | |
| SCHEMBL4187277 | 1.00 | TYR (0.75) | TYRSLC5A1SLC5A2NPC1RAB9A | |
| SCHEMBL4187272 | 1.00 | TYR (0.75) | TYRSLC5A1SLC5A2NPC1RAB9A | |
| SCHEMBL15533442 | 1.00 | TYR (0.75) | TYRSLC5A1SLC5A2NPC1RAB9A | |
| SCHEMBL7744552 | 1.00 | TYR (0.75) | TYRSLC5A1SLC5A2NPC1RAB9A | |
| SCHEMBL18022555 | 1.00 | TYR (0.75) | TYRSLC5A1SLC5A2NPC1RAB9A | |
| SCHEMBL8388035 | 1.00 | TYR (0.75) | TYRSLC5A1SLC5A2NPC1RAB9A | |
| SCHEMBL16689576 | 1.00 | TYR (0.75) | TYRSLC5A1SLC5A2NPC1RAB9A | |
| SCHEMBL15589634 | 1.00 | TYR (0.75) | TYRSLC5A1SLC5A2NPC1RAB9A | |
| SCHEMBL16785939 | 1.00 | TYR (0.75) | TYRSLC5A1SLC5A2NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016041470-A1 | SGLT-2 INHIBITORS | NATIONAL INSTITUTE OF BIOLOGICAL SCIENCES, BEIJING (CN) | 2016-03-24 | — | — | WO | disclosed |