⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10115593 | 0.74 | — | — | |
| SCHEMBL38663901 | 0.74 | — | — | |
| SCHEMBL1358101 | 0.70 | — | — | |
| SCHEMBL14039837 | 0.70 | — | — | |
| SCHEMBL15608631 | 0.70 | — | — | |
| SCHEMBL27993284 | 0.70 | — | — | |
| SCHEMBL17624324 | 0.70 | — | — | |
| SCHEMBL21863292 | 0.69 | POLB (0.35) | — | |
| SCHEMBL13990554 | 0.68 | SMN1; SMN2 (0.39) | — | |
| SCHEMBL24192195 | 0.67 | SMN1; SMN2 (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016044604-A1 | CARM1 INHIBITORS AND USES THEREOF | Epizyme, Inc. (US) | 2016-03-24 | — | — | WO | disclosed |