Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | CHRNB2 | P17787 | 3/20 | 0.39 |
| ▸ | CHRNA3 | P32297 | 3/20 | 0.39 |
| ▸ | CHRNA4 | P43681 | 3/20 | 0.39 |
| ▸ | CHRNB3 | Q05901 | 1/20 | 0.39 |
| ▸ | CHRNA6 | Q15825 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.35 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.33 |
| ▸ | CASP6 | P55212 | 1/20 | 0.32 |
| ▸ | GFER | P55789 | 1/20 | 0.32 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15431899 | 0.78 | CYP1A2 (0.48) | CYP1A2TDP1CHRNB2CHRNA3CHRNA4 | |
| SCHEMBL20434091 | 0.78 | CYP1A2 (0.48) | CYP1A2TDP1CHRNB2CHRNA3CHRNA4 | |
| SCHEMBL17625631 | 0.78 | CYP1A2 (0.48) | CYP1A2TDP1CHRNB2CHRNA3CHRNA4 | |
| SCHEMBL20334409 | 0.78 | JAK3 (0.33) | KMT2A | |
| SCHEMBL25072284 | 0.78 | CYP1A2 (0.43) | CYP1A2TDP1CHRNB2CHRNA3CHRNA4 | |
| SCHEMBL15451884 | 0.75 | CYP1A2 (0.45) | CYP1A2TDP1CHRNB2CHRNA3CHRNA4 | |
| SCHEMBL20434054 | 0.75 | CYP1A2 (0.45) | CYP1A2TDP1CHRNB2CHRNA3CHRNA4 | |
| SCHEMBL25773854 | 0.75 | CYP1A2 (0.45) | CYP1A2TDP1CHRNB2CHRNA3CHRNA4 | |
| SCHEMBL27851213 | 0.75 | USP2 (0.47) | SMN1; SMN2EPHX2EPHX1ALDH1A1HPGD | |
| SCHEMBL15451881 | 0.74 | CYP1A2 (0.43) | CYP1A2TDP1CHRNB2CHRNA3CHRNA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016044585-A1 | ARGININE METHYLTRANSFERASE INHIBITORS AND USES THEREOF | Epizyme, Inc. (US) | 2016-03-24 | — | — | WO | disclosed |