⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20473140 | 0.86 | — | — | |
| SCHEMBL17628479 | 0.85 | — | — | |
| SCHEMBL17628480 | 0.80 | — | — | |
| SCHEMBL28142413 | 0.78 | — | — | |
| SCHEMBL6689944 | 0.67 | — | — | |
| SCHEMBL5451104 | 0.65 | — | — | |
| SCHEMBL17628469 | 0.63 | — | — | |
| SCHEMBL17628470 | 0.63 | — | — | |
| SCHEMBL17628474 | 0.63 | — | — | |
| SCHEMBL17628475 | 0.63 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3197940-B1 | POLYMERIZABLE POLYSILOXANES WITH HYDROPHILIC SUBSTITUENTS | ALCON INC (CH) | 2023-02-15 | — | — | EP | disclosed |
| CN-106716182-B | Polymerizable polysiloxane with hydrophilic substituent | 爱尔康公司 | 2020-06-12 | — | — | CN | disclosed |
| EP-3197940-A1 | POLYMERIZABLE POLYSILOXANES WITH HYDROPHILIC SUBSTITUENTS | Novartis AG (CH) | 2017-08-02 | — | — | EP | disclosed |
| US-9720139-B2 | Polymerizable polysiloxanes with hydrophilic substituents | NOVARTIS AG (CH) | 2017-08-01 | — | — | US | disclosed |
| US-20170176643-A1 | POLYMERIZABLE POLYSILOXANES WITH HYDROPHILIC SUBSTITUENTS | ALCON INC. (CH) | 2017-06-22 | — | — | US | disclosed |
| US-9637582-B2 | Polymerizable polysiloxanes with hydrophilic substituents | NOVARTIS AG (CH) | 2017-05-02 | — | — | US | disclosed |
| US-20160090432-A1 | POLYMERIZABLE POLYSILOXANES WITH HYDROPHILIC SUBSTITUENTS | ALCON INC. (CH) | 2016-03-31 | — | — | US | disclosed |
| WO-2016048853-A1 | POLYMERIZABLE POLYSILOXANES WITH HYDROPHILIC SUBSTITUENTS | NOVARTIS AG (CH) | 2016-03-31 | — | — | WO | disclosed |