Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 1/20 | 0.55 |
| ▸ | MMP2 | P08253 | 2/20 | 0.55 |
| ▸ | MMP7 | P09237 | 1/20 | 0.55 |
| ▸ | MMP9 | P14780 | 1/20 | 0.55 |
| ▸ | MMP12 | P39900 | 1/20 | 0.55 |
| ▸ | MMP13 | P45452 | 1/20 | 0.55 |
| ▸ | MME | P08473 | 2/20 | 0.54 |
| ▸ | TMPRSS11D | O60235 | 1/20 | 0.54 |
| ▸ | CTRL | P40313 | 1/20 | 0.54 |
| ▸ | PSMB5 | P28074 | 4/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.53 |
| ▸ | CYP3A5 | P20815 | 2/20 | 0.53 |
| ▸ | CYP3A7 | P24462 | 2/20 | 0.53 |
| ▸ | CYP3A43 | Q9HB55 | 2/20 | 0.53 |
| ▸ | PSMB9 | P28065 | 2/20 | 0.53 |
| ▸ | PSMB11 | A5LHX3 | 1/20 | 0.53 |
| ▸ | PSMD11 | O00231 | 1/20 | 0.53 |
| ▸ | PSMD12 | O00232 | 1/20 | 0.53 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.53 |
| ▸ | PSMA7 | O14818 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2633256 | 1.00 | ACE (0.55) | ACEMMP2MMP7MMP9MMP12 | |
| SCHEMBL17629489 | 1.00 | ACE (0.55) | ACEMMP2MMP7MMP9MMP12 | |
| SCHEMBL13893311 | 0.90 | BIRC2 (0.54) | TMPRSS11DCTRLPSMB5CYP3A4CYP3A5 | |
| SCHEMBL19474595 | 0.90 | BIRC2 (0.54) | TMPRSS11DCTRLPSMB5CYP3A4CYP3A5 | |
| SCHEMBL84540 | 0.90 | BIRC2 (0.54) | TMPRSS11DCTRLPSMB5CYP3A4CYP3A5 | |
| SCHEMBL13019967 | 0.90 | PSMB5 (0.60) | ACEMMP2MMP7MMP9MMP12 | |
| SCHEMBL85534 | 0.90 | ACE (0.56) | ACEMMP2MMP7MMP9MMP12 | |
| SCHEMBL10080727 | 0.89 | PSMB5 (0.52) | ACEMMP2MMP7MMP9MMP12 | |
| SCHEMBL20873049 | 0.88 | MME (0.64) | ACEMMP2MMP7MMP9MMP12 | |
| SCHEMBL20873050 | 0.88 | MME (0.64) | ACEMMP2MMP7MMP9MMP12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10329325-B2 | Process for the preparation of (S)-4-methyl-N-((S)-1-(((S)-4-methyl-1-((R)-2-methyloxiran-2-yl)-1-oxo-pentan-2-yl) amino)-1-oxo-3-phenylpropan-2-yl)-2-((S)-2-(2-morpholinoacetamido)-4-phenylbutanamido) pentanamide | BIOPHORE INDIA PHARMACEUTICALS PVT. LTD (IN) | 2019-06-25 | — | — | US | disclosed |
| US-20170298093-A1 | Process for the Preparation of (S)-4-Methyl-N-((S)-1-(((S)-4-Methyl-1-((R)-2-Methyloxiran-2-YL)-1-OXO Pentan-2-YL) Amino)-1-OXO-3-Phenylpropan-2-YL)-2-((S)-2-(2-Morpholinoacetamido)-4-Phenylbutanamido) Pentanamide | BIOPHORE INDIA PHARMACEUTICALS PVT. LTD (IN) | 2017-10-19 | — | — | US | disclosed |
| WO-2016046843-A1 | PROCESS FOR THE PREPARATION OF (S)-4-METHYL-N-((S)-1-(((S)-4-METHYL-1-((R)-2-METHYLOXIRAN-2-YL)-1-OXO PENTAN-2-YL) AMINO)-1-OXO-3-PHENYLPROPAN-2-YL)-2-((S)-2-(2-MORPHOLINOACETAMIDO)-4-PHENYLBUTANAMIDO) PENTANAMIDE | BIOPHORE INDIA PHARMACEUTICALS PVT. LTD. (IN) | 2016-03-31 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170298093-A1 | Process for the Preparation of (S)-4-Methyl-N-((S)-1-(((S)-4-Methyl-1-((R)-2-Methyloxiran-2-YL)-1-OXO Pentan-2-YL) Amino)-1-OXO-3-Phenylpropan-2-YL)-2-((S)-2-(2-Morpholinoacetamido)-4-Phenylbutanamido) Pentanamide | PSMA1, PSMA2, PSMA6 | ACE 624/4885MMP2 2236/4885MMP7 2283/4885 |
| US-10329325-B2 | Process for the preparation of (S)-4-methyl-N-((S)-1-(((S)-4-methyl-1-((R)-2-methyloxiran-2-yl)-1-oxo-pentan-2-yl) amino)-1-oxo-3-phenylpropan-2-yl)-2-((S)-2-(2-morpholinoacetamido)-4-phenylbutanamido) pentanamide | PSMA1, PSMA2, PSMA3 | ACE 632/4885MMP2 2561/4885MMP7 2394/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.