Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 1/20 | 0.67 |
| ▸ | GSTK1 | Q9Y2Q3 | 1/20 | 0.67 |
| ▸ | GLO1 | Q04760 | 4/20 | 0.47 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.43 |
| ▸ | NOD1 | Q9Y239 | 2/20 | 0.37 |
| ▸ | FNTA | P49354 | 3/20 | 0.36 |
| ▸ | FNTB | P49356 | 3/20 | 0.36 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.36 |
| ▸ | ACE | P12821 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | RIMKLA | Q8IXN7 | 1/20 | 0.35 |
| ▸ | NAALAD2 | Q9Y3Q0 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29623583 | 0.92 | PTGS1 (0.71) | PTGS1GSTK1GLO1FOLH1NOD1 | |
| SCHEMBL27490732 | 0.90 | PTGS1 (0.72) | PTGS1GSTK1GLO1FOLH1NOD1 | |
| SCHEMBL29559136 | 0.90 | PTGS1 (0.72) | PTGS1GSTK1GLO1FOLH1NOD1 | |
| SCHEMBL31473339 | 0.89 | PTGS1 (0.67) | PTGS1GSTK1GLO1FOLH1NOD1 | |
| SCHEMBL25261524 | 0.86 | PTGS1 (0.67) | PTGS1GSTK1GLO1FOLH1NOD1 | |
| SCHEMBL235441 | 0.86 | PTGS1 (0.67) | PTGS1GSTK1GLO1FOLH1NOD1 | |
| SCHEMBL1646531 | 0.86 | PTGS1 (0.71) | PTGS1GSTK1GLO1FOLH1NOD1 | |
| SCHEMBL1332941 | 0.86 | PTGS1 (0.71) | PTGS1GSTK1GLO1FOLH1NOD1 | |
| SCHEMBL28862930 | 0.86 | PTGS1 (0.71) | PTGS1GSTK1GLO1FOLH1NOD1 | |
| SCHEMBL28524138 | 0.86 | PTGS1 (0.71) | PTGS1GSTK1GLO1FOLH1NOD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016046782-A1 | IMIDAZOLE BIARYL COMPOUNDS AS S-NITROSOGLUTATHIONE REDUCTASE INHIBITORS | GLENMARK PHARMACEUTICALS S.A. (CH) | 2016-03-31 | — | — | WO | disclosed |