Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | PLA2G2C | Q5R387 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 4/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.31 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.31 |
| ▸ | GMNN | O75496 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | THPO | P40225 | 1/20 | 0.31 |
| ▸ | MTOR | P42345 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5190797 | 0.98 | MEN1 (0.40) | MEN1KMT2AHTTMAPTTHRB | |
| SCHEMBL4398138 | 0.98 | MEN1 (0.40) | MEN1KMT2AHTTMAPTTHRB | |
| SCHEMBL5189224 | 0.98 | MEN1 (0.40) | MEN1KMT2AHTTMAPTTHRB | |
| SCHEMBL21006 | 0.91 | USP2 (0.42) | MEN1KMT2AHTTMAPTTHRB | |
| SCHEMBL5190830 | 0.89 | CNR2 (0.42) | MEN1KMT2AMAPTTHRBALDH1A1 | |
| SCHEMBL4204713 | 0.89 | USP2 (0.44) | MEN1KMT2AHTTMAPTTHRB | |
| SCHEMBL4204839 | 0.89 | USP2 (0.44) | MEN1KMT2AHTTMAPTTHRB | |
| SCHEMBL28823669 | 0.89 | USP2 (0.44) | MEN1KMT2AHTTMAPTTHRB | |
| SCHEMBL303130 | 0.89 | USP2 (0.44) | MEN1KMT2AHTTMAPTTHRB | |
| SCHEMBL28869452 | 0.89 | USP2 (0.44) | MEN1KMT2AHTTMAPTTHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1781593-B1 | CATIONIC LIPIDS AND METHODS OF USE | PROTIVA BIOTHERAPEUTICS INC (CA) | 2011-12-14 | — | — | EP | claimed |
| EP-2611461-A1 | PEGYLATED LIPOSOMES FOR DELIVERY OF IMMUNOGEN-ENCODING RNA | Novartis AG (CH) | 2013-07-10 | — | — | EP | disclosed |
| WO-2012031043-A1 | PEGYLATED LIPOSOMES FOR DELIVERY OF IMMUNOGEN-ENCODING RNA | NOVARTIS AG (CH) | 2012-03-08 | — | — | WO | disclosed |