⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10768521 | 0.93 | — | — | |
| SCHEMBL1290618 | 0.76 | — | — | |
| SCHEMBL259934 | 0.76 | — | — | |
| SCHEMBL1358818 | 0.67 | — | — | |
| SCHEMBL6233086 | 0.67 | — | — | |
| SCHEMBL1203338 | 0.65 | — | — | |
| SCHEMBL1150048 | 0.65 | TDP1 (0.43) | — | |
| SCHEMBL6381874 | 0.65 | — | — | |
| SCHEMBL6971896 | 0.64 | — | — | |
| SCHEMBL11790662 | 0.62 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 75 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110612119-A | Phospholipid ether (PLE) CAR T cell tumor targeting (CTCT) agents | 西雅图儿童医院（DBA西雅图儿童研究所） | 2019-12-24 | — | — | CN | claimed |
| US-8614312-B2 | Method for preparing nucleotides and related analogues by synthesis on soluble substrate, and biological tools thus prepared | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2013-12-24 | — | — | US | claimed |
| US-20110118454-A1 | METHOD FOR PREPARING NUCLEOTIDES AND RELATED ANALOGUES BY SYNTHESIS ON SOLUBLE SUBSTRATE, AND BIOLOGICAL TOOLS THUS PREPARED | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2011-05-19 | — | — | US | claimed |
| EP-2265624-A1 | METHOD FOR PREPARING NUCLEOTIDES AND RELATED ANALOGUES BY SYNTHESIS ON SOLUBLE SUBSTRATE, AND BIOLOGICAL TOOLS THUS PREPARED | Centre National de la Recherche Scientifique (FR) | 2010-12-29 | — | — | EP | claimed |
| WO-2009115694-A1 | METHOD FOR PREPARING NUCLEOTIDES AND RELATED ANALOGUES BY SYNTHESIS ON SOLUBLE SUBSTRATE, AND BIOLOGICAL TOOLS THUS PREPARED | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2009-09-24 | — | — | WO | claimed |
| JP-9328493-A | — | — | None | — | — | JP | disclosed |
| JP-4342551-A | — | — | None | — | — | JP | disclosed |
| CN-110612119-B | Phosphatidylether (PLE) CAR T cell tumor targeting (CTCT) agents | 西雅图儿童医院（DBA西雅图儿童研究所） | 2024-10-29 | — | — | CN | disclosed |
| US-20230322925-A1 | PHOSPHOLIPID ETHER (PLE) CAR T CELL TUMOR TARGETING (CTCT) AGENTS | SEATTLE CHILDREN’S HOSPITAL DBA SEATTLE CHILDREN’S RES INSTITUTE (US) | 2023-10-12 | — | — | US | disclosed |
| US-11649288-B2 | Phospholipid ether (PLE) CAR T cell tumor targeting (CTCT) agents | SEATTLE CHILDREN'S HOSPITAL (US) | 2023-05-16 | — | — | US | disclosed |
| US-20200087399-A1 | PHOSPHOLIPID ETHER (PLE) CAR T CELL TUMOR TARGETING (CTCT) AGENTS | Seattle Children's Hospital (dba Seattle Children's Research Institute) | 2020-03-19 | — | — | US | disclosed |
| CN-110612119-A | Phospholipid ether (PLE) CAR T cell tumor targeting (CTCT) agents | 西雅图儿童医院（DBA西雅图儿童研究所） | 2019-12-24 | — | — | CN | disclosed |
| EP-0234820-A2 | A process for producing 0,0-dilower-alkylchlorothiophosphate | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1987-09-02 | — | — | EP | disclosed |
| US-4473562-A | INSECTICIDE | CHEVRON RESEARCH COMPANY (US) | 1984-09-25 | — | — | US | disclosed |
| US-4382087-A | Selected O-(2-trichloromethyl-4-pyrimidinyl)-O,O-dialkyl phosphorothionates and O-(2-trichloromethyl-4-pyrimidinyl)-O,O-dialkyl phosphoronates and their use as insecticides | OLIN CORPORATION (US) | 1983-05-03 | — | — | US | disclosed |
| US-4309422-A | INSECTICIDES | VELSICOL CHEMICAL CORPORATION (US) | 1982-01-05 | — | — | US | disclosed |
| US-4203932-A | INSECTICIDES, MITICIDES | GAF CORPORATION (US) | 1980-05-20 | — | — | US | disclosed |
| US-4203979-A | MITICIDES | GAF CORPORATION (US) | 1980-05-20 | — | — | US | disclosed |
| US-4069319-A | 3-(DIALKYLPHOSPHORYL- OR THIOPHOSPHORYL-OXY)-1,2,4-THIADIAZOLES; INSECTICIDES, NEMATOCIDES | ROUSSEL UCLAF (FR) | 1978-01-17 | — | — | US | disclosed |
| US-4006229-A | Insecticidal and acaricidal trihalophenyl thiophosphates | CIBA-GEIGY AG (CH) | 1977-02-01 | — | — | US | disclosed |