Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC17A5 | Q9NRA2 | 1/20 | 0.49 |
| ▸ | MDM4 | O15151 | 3/20 | 0.47 |
| ▸ | TP53 | P04637 | 3/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.46 |
| ▸ | CASP3 | P42574 | 2/20 | 0.44 |
| ▸ | CASP1 | P29466 | 2/20 | 0.44 |
| ▸ | TLR2 | O60603 | 2/20 | 0.43 |
| ▸ | MDM2 | Q00987 | 5/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17633370 | 0.88 | MDM2 (0.51) | MDM4TP53HDAC1HDAC2CASP3 | |
| SCHEMBL29624261 | 0.86 | SLC17A5 (0.49) | SLC17A5MDM4TP53CASP3CASP1 | |
| SCHEMBL5060938 | 0.86 | KMT2A (0.51) | SLC17A5MDM4TP53HDAC1HDAC2 | |
| SCHEMBL13716717 | 0.85 | SLC17A5 (0.48) | SLC17A5MDM4TP53CASP3CASP1 | |
| SCHEMBL15280776 | 0.85 | KMT2A (0.51) | MDM4TP53CASP3CASP1TLR2 | |
| SCHEMBL29398585 | 0.85 | KMT2A (0.51) | MDM4TP53CASP3CASP1TLR2 | |
| SCHEMBL30471287 | 0.85 | KMT2A (0.51) | MDM4TP53CASP3CASP1TLR2 | |
| SCHEMBL29401691 | 0.85 | KMT2A (0.51) | MDM4TP53CASP3CASP1TLR2 | |
| SCHEMBL28510322 | 0.85 | KMT2A (0.51) | MDM4TP53CASP3CASP1TLR2 | |
| SCHEMBL10173082 | 0.85 | KMT2A (0.51) | MDM4TP53CASP3CASP1TLR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3197481-A1 | STABILIZED ADRENOMEDULLIN DERIVATIVES AND USE THEREOF | Bayer Pharma Aktiengesellschaft (DE) | 2017-08-02 | — | — | EP | disclosed |
| WO-2016046301-A1 | STABILIZED ADRENOMEDULLIN DERIVATIVES AND USE THEREOF | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2016-03-31 | — | — | WO | disclosed |