Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 3/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.32 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.32 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.32 |
| ▸ | LTA4H | P09960 | 2/20 | 0.31 |
| ▸ | RAB9A | P51151 | 3/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.31 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 2/20 | 0.30 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17633927 | 0.94 | CA12 (0.33) | CYP3A4LTA4HLMNANR5A1CHRM1 | |
| SCHEMBL17633676 | 0.92 | NR5A1 (0.36) | LTA4HLMNANR5A1CHRM1 | |
| SCHEMBL17633741 | 0.86 | — | — | |
| SCHEMBL17633672 | 0.83 | CYP3A4 (0.32) | CYP2D6CYP3A4ADRB2ADRB1ADRB3 | |
| SCHEMBL17633733 | 0.80 | CYP3A4 (0.30) | CYP2D6CYP3A4 | |
| SCHEMBL19282895 | 0.80 | NR5A1 (0.31) | CYP2D6CYP3A4LTA4HNR5A1 | |
| SCHEMBL17633851 | 0.79 | PSMB5 (0.33) | — | |
| SCHEMBL17633826 | 0.78 | CHRM1 (0.33) | LTA4HNR5A1CHRM1 | |
| SCHEMBL17633775 | 0.77 | TSHR (0.34) | — | |
| SCHEMBL17633776 | 0.77 | TSHR (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11028256-B2 | Silica-containing rubber compositions containing specified coupling agents and related methods | BRIDGESTONE AMERICAS TIRE OPERATIONS, LLC (US) | 2021-06-08 | — | — | US | disclosed |
| US-20200123349-A1 | SILICA-CONTAINING RUBBER COMPOSITIONS CONTAINING SPECIFIED COUPLING AGENTS AND RELATED METHODS | BRIDGESTONE AMERICAS TIRE OPERATIONS, LLC (US) | 2020-04-23 | — | — | US | disclosed |
| US-20170247532-A1 | SILICA-CONTAINING RUBBER COMPOSITIONS CONTAINING SPECIFIED COUPLING AGENTS AND RELATED METHODS | BRIDGESTONE AMERICAS TIRE OPERATIONS, LLC | 2017-08-31 | — | — | US | disclosed |
| EP-3197950-A1 | SILICA-CONTAINING RUBBER COMPOSITIONS CONTAINING SPECIFIED COUPLING AGENTS AND RELATED METHODS | Bridgestone Americas Tire Operations, LLC (US) | 2017-08-02 | — | — | EP | disclosed |
| WO-2016048935-A1 | SILICA-CONTAINING RUBBER COMPOSITIONS CONTAINING SPECIFIED COUPLING AGENTS AND RELATED METHODS | BRIDGESTONE AMERICAS TIRE OPERATIONS, LLC (US) | 2016-03-31 | — | — | WO | disclosed |