SCHEMBL17633906

SCHEMBL17633906

CCCCCCCCCCCCCCCC(=O)NC(CCC(=O)ON1C(=O)CCC1=O)C(=O)OC(C)(C)C

nearest known ligand 0.46

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 4/20 0.46
NOD1 Q9Y239 9/20 0.42
POLB P06746 1/20 0.42
PLA2G2C Q5R387 1/20 0.37
MEN1 O00255 1/20 0.36
FAAH O00519 1/20 0.36
MAPK1 P28482 1/20 0.36
DNM1 Q05193 1/20 0.36
BCHE P06276 1/20 0.36
ACHE P22303 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
PLA2G10 O15496 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL344852 1.00 KMT2A (0.46) KMT2ANOD1POLBPLA2G2CMEN1
SCHEMBL337876 1.00 KMT2A (0.46) KMT2ANOD1POLBPLA2G2CMEN1
SCHEMBL337914 1.00 KMT2A (0.46) KMT2ANOD1POLBPLA2G2CMEN1
SCHEMBL334606 1.00 KMT2A (0.46) KMT2ANOD1POLBPLA2G2CMEN1
SCHEMBL16539029 1.00 KMT2A (0.46) KMT2ANOD1POLBPLA2G2CMEN1
SCHEMBL336557 1.00 KMT2A (0.46) KMT2ANOD1POLBPLA2G2CMEN1
SCHEMBL4821245 1.00 KMT2A (0.46) KMT2ANOD1POLBPLA2G2CMEN1
SCHEMBL18378739 0.99 KMT2A (0.46) KMT2ANOD1POLBPLA2G2CMEN1
SCHEMBL24819248 0.93 KMT2A (0.44) KMT2ANOD1POLBL3MBTL1SMN1; SMN2
SCHEMBL20467657 0.93 KMT2A (0.44) KMT2ANOD1POLBL3MBTL1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110023329-B Novel compounds as peptide triple GLP 1/glucagon/GIP receptor agonists 赛诺菲 2024-05-03 CN disclosed
CN-116836258-A Solid phase synthesis method of liraglutide 辽宁药联制药有限公司 2023-10-03 CN disclosed
EP-3548508-B1 NEW COMPOUNDS AS PEPTIDIC TRIGONAL GLP1/GLUCAGON/GIP RECEPTOR AGONISTS SANOFI SA (FR) 2021-10-27 EP disclosed
CN-111892650-A Solid-phase synthesis method of liraglutide 辽宁药联制药有限公司 2020-11-06 CN disclosed
CN-110023329-A Noval chemical compound as the triple GLP1/ glucagon/GIP receptor stimulating agents of peptides 赛诺菲 2019-07-16 CN disclosed
US-20190177392-A1 SYNTHESIS OF GLP-1 PEPTIDES NOVETIDE LTD (IL) 2019-06-13 US disclosed
US-20180155406-A1 COMPOUNDS AS PEPTIDIC TRIGONAL GLP1/GLUCAGON/GIP RECEPTOR AGONISTS SANOFI (FR) 2018-06-07 US disclosed
US-20180057558-A1 Synthesis of GLP-1 Peptides NOVETIDE, LTD. (IL) 2018-03-01 US disclosed
EP-3221342-A1 SYNTHESIS OF GLP-1 PEPTIDES Novetide Ltd. (IL) 2017-09-27 EP disclosed
WO-2016046753-A1 SYNTHESIS OF GLP-1 PEPTIDES NOVETIDE, LTD. (IL) 2016-03-31 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190177392-A1 SYNTHESIS OF GLP-1 PEPTIDES GLP1R, GIPR, IAPP KMT2A 2774/4885NOD1 365/4885POLB 3820/4885
US-20180057558-A1 Synthesis of GLP-1 Peptides GLP1R, GIPR, IAPP KMT2A 2774/4885NOD1 365/4885POLB 3820/4885
US-20180155406-A1 COMPOUNDS AS PEPTIDIC TRIGONAL GLP1/GLUCAGON/GIP RECEPTOR AGONISTS GLP1R, GIPR, GCGR KMT2A 4117/4885NOD1 1688/4885POLB 4868/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.