Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16108153 | 0.87 | NAMPT (0.64) | NAMPTCYP2C9 | |
| SCHEMBL12467920 | 0.78 | NAMPT (0.68) | NAMPTCYP2C9 | |
| SCHEMBL176197 | 0.78 | NAMPT (0.58) | NAMPTCYP2C9 | |
| SCHEMBL12467855 | 0.76 | NAMPT (0.79) | NAMPTCYP2C9 | |
| SCHEMBL173717 | 0.76 | NAMPT (0.77) | NAMPTCYP2C9 | |
| SCHEMBL16108087 | 0.76 | NAMPT (0.66) | NAMPTCYP2C9 | |
| SCHEMBL12468117 | 0.74 | NAMPT (0.75) | NAMPTCYP2C9 | |
| SCHEMBL12467918 | 0.74 | NAMPT (0.81) | NAMPTCYP2C9 | |
| SCHEMBL170791 | 0.74 | NAMPT (0.68) | NAMPTCYP2C9 | |
| SCHEMBL174669 | 0.73 | NAMPT (0.71) | NAMPTCYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2611804-A1 | NOVEL COMPOUNDS AND COMPOSITIONS FOR THE INHIBITION OF NAMPT | Forma TM, LLC. (US) | 2013-07-10 | — | — | EP | disclosed |
| WO-2012031197-A1 | NOVEL COMPOUNDS AND COMPOSITIONS FOR THE INHIBITION OF NAMPT | FORMA THERAPEUTICS, INC. (US) | 2012-03-08 | — | — | WO | disclosed |