Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 20/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10154551 | 0.89 | BACE1 (0.40) | BACE1 | |
| SCHEMBL10154568 | 0.89 | BACE1 (0.39) | BACE1 | |
| SCHEMBL10154482 | 0.88 | BACE1 (0.47) | BACE1 | |
| SCHEMBL14980730 | 0.88 | BACE1 (0.37) | BACE1 | |
| SCHEMBL4078345 | 0.84 | BACE1 (0.38) | BACE1 | |
| SCHEMBL4074208 | 0.84 | BACE1 (0.48) | BACE1 | |
| SCHEMBL10154545 | 0.84 | BACE1 (0.48) | BACE1 | |
| SCHEMBL13306293 | 0.83 | BACE1 (0.42) | BACE1 | |
| SCHEMBL4074715 | 0.77 | BACE1 (0.49) | BACE1 | |
| SCHEMBL4077651 | 0.77 | BACE1 (0.49) | BACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2597087-B1 | Dihydrooxazine and tetrahydropyrimidine derivatives as BACE 1 inhibitors | SHIONOGI & CO (JP) | 2016-03-30 | — | — | EP | disclosed |