Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 13/20 | 0.70 |
| ▸ | MEN1 | O00255 | 12/20 | 0.70 |
| ▸ | UGCG | Q16739 | 3/20 | 0.70 |
| ▸ | TP53 | P04637 | 2/20 | 0.70 |
| ▸ | MAPT | P10636 | 2/20 | 0.70 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.70 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.70 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.70 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.70 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.70 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.70 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.70 |
| ▸ | MTOR | P42345 | 1/20 | 0.70 |
| ▸ | LMNA | P02545 | 2/20 | 0.69 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.69 |
| ▸ | GMNN | O75496 | 1/20 | 0.69 |
| ▸ | BLM | P54132 | 1/20 | 0.69 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.69 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.69 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5075622 | 1.00 | KMT2A (0.70) | KMT2AMEN1UGCGTP53MAPT | |
| SCHEMBL857438 | 0.99 | KMT2A (0.68) | KMT2AMEN1UGCGTP53MAPT | |
| SCHEMBL7683399 | 0.90 | UGCG (0.69) | KMT2AMEN1UGCGTP53MAPT | |
| SCHEMBL12000798 | 0.82 | UGCG (1.00) | KMT2AMEN1UGCGTP53MAPT | |
| SCHEMBL137622 | 0.82 | UGCG (1.00) | KMT2AMEN1UGCGTP53MAPT | |
| SCHEMBL23845860 | 0.82 | UGCG (1.00) | KMT2AMEN1UGCGTP53MAPT | |
| SCHEMBL723342 | 0.82 | UGCG (1.00) | KMT2AMEN1UGCGTP53MAPT | |
| SCHEMBL13460643 | 0.82 | UGCG (1.00) | KMT2AMEN1UGCGTP53MAPT | |
| SCHEMBL14304968 | 0.82 | UGCG (1.00) | KMT2AMEN1UGCGTP53MAPT | |
| SCHEMBL295573 | 0.82 | UGCG (1.00) | KMT2AMEN1UGCGTP53MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2349255-B1 | 2-ACYLAMINOPROPOANOL-TYPE GLUCOSYLCERAMIDE SYNTHASE INHIBITORS | GENZYME CORP (US) | 2016-03-30 | — | — | EP | disclosed |