Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Arginine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OTC | P00480 | 1/20 | 0.38 |
| ▸ | DDAH1 | O94760 | 1/20 | 0.36 |
| ▸ | ARG1 | P05089 | 1/20 | 0.36 |
| ▸ | NPY4R | P50391 | 7/20 | 0.34 |
| ▸ | NPY1R | P25929 | 5/20 | 0.34 |
| ▸ | NPY2R | P49146 | 4/20 | 0.34 |
| ▸ | NPY5R | Q15761 | 4/20 | 0.34 |
| ▸ | NOS3 | P29474 | 1/20 | 0.34 |
| ▸ | NOS1 | P29475 | 1/20 | 0.34 |
| ▸ | NOS2 | P35228 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Arginine SCHEMBL17113851 | 1.00 | OTC (0.38) | OTCDDAH1ARG1NPY4RNPY1R | |
| Arginine SCHEMBL17113847 | 1.00 | OTC (0.38) | OTCDDAH1ARG1NPY4RNPY1R | |
| Arginine SCHEMBL176372 | 1.00 | OTC (0.38) | OTCDDAH1ARG1NPY4RNPY1R | |
| Arginine SCHEMBL15194711 | 1.00 | OTC (0.38) | OTCDDAH1ARG1NPY4RNPY1R | |
| Arginine SCHEMBL1537331 | 1.00 | OTC (0.38) | OTCDDAH1ARG1NPY4RNPY1R | |
| Arginine SCHEMBL23242196 | 1.00 | OTC (0.38) | OTCDDAH1ARG1NPY4RNPY1R | |
| Arginine SCHEMBL17113849 | 1.00 | OTC (0.38) | OTCDDAH1ARG1NPY4RNPY1R | |
| Arginine SCHEMBL13730532 | 1.00 | OTC (0.38) | OTCDDAH1ARG1NPY4RNPY1R | |
| Arginine SCHEMBL21273831 | 1.00 | OTC (0.38) | OTCDDAH1ARG1NPY4RNPY1R | |
| Arginine SCHEMBL28235439 | 0.99 | OTC (0.37) | OTCDDAH1ARG1NPY4RNPY1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1112 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11884700-B2 | Methods of inactivating viral contaminants | Ichnos Sciences SA (CH) | 2024-01-30 | — | — | US | claimed |
| US-20220112237-A1 | AMINO ACID COMPOSITION HAVING CO-AMORPHOUS STRUCTURE | AJINOMOTO CO., INC. (JP) | 2022-04-14 | — | — | US | claimed |
| US-20210324000-A1 | METHODS OF INACTIVATING VIRAL CONTAMINANTS | IGI Therapeutics SA (CH) | 2021-10-21 | — | — | US | claimed |
| US-20200369747-A1 | METHODS OF INACTIVATING VIRAL CONTAMINANTS | Ichnos Sciences SA. (CH) | 2020-11-26 | — | — | US | claimed |
| EP-3672637-A1 | METHODS OF INACTIVATING VIRAL CONTAMINANTS | Ichnos Sciences SA (CH) | 2020-07-01 | — | — | EP | claimed |
| US-20190292221-A1 | METHODS OF INACTIVATING VIRAL CONTAMINANTS | GLENMARK PHARMACEUTICALS S.A. (CH) | 2019-09-26 | — | — | US | claimed |
| WO-2019038742-A1 | METHODS OF INACTIVATING VIRAL CONTAMINANTS | GLENMARK PHARMACEUTICALS SA (CH) | 2019-02-28 | — | — | WO | claimed |
| EP-3245296-A1 | IN VITRO METHOD FOR ESTIMATING IN VIVO PROTEIN DIGESTIBILITY | General Mills, Inc. (US) | 2017-11-22 | — | — | EP | claimed |
| WO-2016115249-A1 | IN VITRO METHOD FOR ESTIMATING IN VIVO PROTEIN DIGESTIBILITY | GENERAL MILLS, INC. (US) | 2016-07-21 | — | — | WO | claimed |
| CN-105431167-A | Non-naturally occurring factor h binding proteins (FHBP) and methods of use thereof | CHILDREN'S HOSPITAL & RES CENTER OAKLAND | 2016-03-23 | — | — | CN | claimed |
| CN-102321140-A | Lipoid cation function molecule synthesized from natural cholesterol and amino acid and preparation method and application thereof | SHANGHAI INST ORGANIC CHEM | 2012-01-18 | — | — | CN | claimed |
| EP-1481052-B1 | HYALURONAN SYNTHASE GENES AND EXPRESSION THEREOF | UNIV OKLAHOMA STATE (US) | 2010-06-09 | — | — | EP | claimed |
| JP-2009529509-A | — | — | 2009-08-20 | — | — | JP | claimed |
| EP-2007791-A2 | MODIFIED MOLECULES WHICH PROMOTE HEMATOPOIESIS | AplaGen GmbH (DE) | 2008-12-31 | — | — | EP | claimed |
| WO-2007101698-A2 | MODIFIED MOLECULES WHICH PROMOTE HEMATOPOIESIS | APLAGEN GMBH (DE) | 2007-09-13 | — | — | WO | claimed |
| EP-0523189-B1 | CATIONIC LIPIDS FOR INTRACELLULAR DELIVERY OF BIOLOGICALLY ACTIVE MOLECULES | VICAL INC (US) | 1999-06-16 | — | — | EP | claimed |
| EP-0717753-A1 | RIBOSOME INACTIVATING PROTEINS EXTRACTED FROM SEEDS OF SAPONARIA OCYMOIDES AND VACCARIA PYRAMIDATA, THEIR PREPARATION AND IMMUNOTOXINS CONTAINING THEM | Menarini Ricerche S.p.A. (IT) | 1996-06-26 | — | — | EP | claimed |
| WO-1995007297-A1 | RIBOSOME INACTIVATING PROTEINS EXTRACTED FROM SEEDS OF SAPONARIA OCYMOIDES AND VACCARIA PYRAMIDATA, THEIR PREPARATION AND IMMUNOTOXINS CONTAINING THEM | MENARINI RICERCHE SUD S.P.A. (IT) | 1995-03-16 | — | — | WO | claimed |
| EP-0175871-B1 | PROCESS FOR IMPROVING OR MODIFYING THE TASTE AND AROMA OF CITRUS FRUIT COMPOSITIONS | FIRMENICH SA (CH) | 1988-03-23 | — | — | EP | claimed |
| EP-0175871-A1 | Process for improving or modifying the taste and aroma of citrus fruit compositions | FIRMENICH SA (CH) | 1986-04-02 | — | — | EP | claimed |