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SCHEMBL17640497

SCHEMBL17640497

CS1(C)c2ccccc2N(c2ccc(-c3nc(-c4ccccc4)nn3-c3ccccc3)cc2)c2ccccc21

nearest known ligand 0.51

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
▸ NR1H2 P55055 5/20 0.41
▸ NR1H3 Q13133 5/20 0.41
▸ NPC1 O15118 1/20 0.41
▸ RAB9A P51151 1/20 0.41
▸ SMN1; SMN2 Q16637 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17640519 0.91 NR1H3 (0.34) NR1H2NR1H3NPC1RAB9ASMN1; SMN2
SCHEMBL19499729 0.87 SMN1; SMN2 (0.48) NR1H2NR1H3NPC1RAB9ASMN1; SMN2
SCHEMBL17640503 0.87 SMN1; SMN2 (0.48) NR1H2NR1H3NPC1RAB9ASMN1; SMN2
SCHEMBL17640491 0.87 SMN1; SMN2 (0.48) NR1H2NR1H3NPC1RAB9ASMN1; SMN2
SCHEMBL17640391 0.87 SMN1; SMN2 (0.48) NR1H2NR1H3NPC1RAB9ASMN1; SMN2
SCHEMBL17640500 0.87 SMN1; SMN2 (0.39) NR1H2NR1H3NPC1RAB9ASMN1; SMN2
SCHEMBL17640493 0.87 SMN1; SMN2 (0.39) NR1H2NR1H3NPC1RAB9ASMN1; SMN2
SCHEMBL19499723 0.86 SMN1; SMN2 (0.45) NR1H2NR1H3NPC1RAB9ASMN1; SMN2
SCHEMBL19499720 0.86 SMN1; SMN2 (0.45) NR1H2NR1H3NPC1RAB9ASMN1; SMN2
SCHEMBL17640393 0.86 SMN1; SMN2 (0.49) NR1H2NR1H3NPC1RAB9ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2016046350-A1 FLUORESCENT ORGANIC LIGHT EMITTING ELEMENTS HAVING HIGH EFFICIENCY BASF SE (DE) 2016-03-31 — — WO disclosed
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