Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H4 | Q96RI1 | 3/20 | 0.58 |
| ▸ | RAB9A | P51151 | 9/20 | 0.54 |
| ▸ | NPC1 | O15118 | 7/20 | 0.54 |
| ▸ | NFKB1 | P19838 | 4/20 | 0.54 |
| ▸ | NFKB2 | Q00653 | 4/20 | 0.54 |
| ▸ | RELA | Q04206 | 4/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 11/20 | 0.52 |
| ▸ | MAPT | P10636 | 6/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.52 |
| ▸ | MEN1 | O00255 | 4/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | PKM | P14618 | 3/20 | 0.50 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 5/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CA2 | P00918 | 2/20 | 0.48 |
| ▸ | CA9 | Q16790 | 2/20 | 0.48 |
| ▸ | CA12 | O43570 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17640537 | 1.00 | NR1H4 (0.58) | NR1H4RAB9ANPC1NFKB1NFKB2 | |
| SCHEMBL17640527 | 0.97 | NR1H4 (0.53) | NR1H4RAB9ANPC1NFKB1NFKB2 | |
| SCHEMBL17640607 | 0.96 | NR1H4 (0.51) | NR1H4RAB9ANPC1NFKB1NFKB2 | |
| SCHEMBL17640609 | 0.89 | NR1H4 (0.44) | NR1H4RAB9ANPC1NFKB1NFKB2 | |
| SCHEMBL17640566 | 0.88 | NR1H4 (0.66) | NR1H4RAB9ANPC1NFKB1NFKB2 | |
| SCHEMBL17640553 | 0.88 | NR1H4 (0.66) | NR1H4RAB9ANPC1NFKB1NFKB2 | |
| SCHEMBL17640623 | 0.87 | NPC1 (0.44) | NR1H4RAB9ANPC1NFKB1NFKB2 | |
| SCHEMBL17640531 | 0.87 | NR1H4 (0.62) | NR1H4RAB9ANPC1NFKB1NFKB2 | |
| SCHEMBL16271063 | 0.85 | P2RX4 (0.40) | NR1H4RAB9ANPC1SMN1; SMN2MAPT | |
| SCHEMBL16271052 | 0.85 | P2RX4 (0.40) | NR1H4RAB9ANPC1SMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016046350-A1 | FLUORESCENT ORGANIC LIGHT EMITTING ELEMENTS HAVING HIGH EFFICIENCY | BASF SE (DE) | 2016-03-31 | — | — | WO | disclosed |