Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 20/20 | 0.64 |
| ▸ | PIK3R2 | O00459 | 8/20 | 0.62 |
| ▸ | PIK3CG | P48736 | 9/20 | 0.49 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.47 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19307648 | 0.90 | PIK3CD (0.79) | PIK3CDPIK3R2PIK3CGPIK3CBPIK3R1 | |
| SCHEMBL19307683 | 0.90 | PIK3CD (0.79) | PIK3CDPIK3R2PIK3CGPIK3CBPIK3R1 | |
| SCHEMBL19307647 | 0.90 | PIK3CD (0.79) | PIK3CDPIK3R2PIK3CGPIK3CBPIK3R1 | |
| SCHEMBL20964211 | 0.88 | PIK3CD (0.81) | PIK3CDPIK3R2PIK3CGPIK3CBPIK3R1 | |
| SCHEMBL19307583 | 0.88 | PIK3CD (0.81) | PIK3CDPIK3R2PIK3CGPIK3CBPIK3R1 | |
| SCHEMBL19307582 | 0.88 | PIK3CD (0.81) | PIK3CDPIK3R2PIK3CGPIK3CBPIK3R1 | |
| SCHEMBL17640659 | 0.81 | PIK3CD (0.54) | PIK3CDPIK3R2PIK3CGPIK3CBPIK3R1 | |
| SCHEMBL19307652 | 0.81 | PIK3CD (0.72) | PIK3CDPIK3R2PIK3CG | |
| SCHEMBL19307651 | 0.81 | PIK3CD (0.72) | PIK3CDPIK3R2PIK3CG | |
| SCHEMBL20964109 | 0.78 | PIK3CD (1.00) | PIK3CDPIK3R2PIK3CGPIK3CBPIK3R1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016045591-A1 | NOVEL IMIDAZOPYRIDAZINE COMPOUNDS AND THEIR USE | HUTCHISON MEDIPHARMA LIMITED (CN) | 2016-03-31 | — | — | WO | disclosed |