Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.63 |
| ▸ | MEN1 | O00255 | 2/20 | 0.63 |
| ▸ | MAPT | P10636 | 2/20 | 0.63 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.60 |
| ▸ | GAA | P10253 | 2/20 | 0.60 |
| ▸ | POLB | P06746 | 2/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.59 |
| ▸ | HPGD | P15428 | 1/20 | 0.59 |
| ▸ | HTT | P42858 | 1/20 | 0.58 |
| ▸ | AKT1 | P31749 | 2/20 | 0.53 |
| ▸ | RAB9A | P51151 | 2/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17643014 | 0.93 | KMT2A (0.74) | KMT2AMEN1MAPTHSP90AA1ALDH1A1 | |
| SCHEMBL21658325 | 0.91 | KMT2A (0.77) | KMT2AMEN1MAPTHSP90AA1ALDH1A1 | |
| SCHEMBL17643387 | 0.90 | KMT2A (0.74) | KMT2AMEN1MAPTHSP90AA1ALDH1A1 | |
| SCHEMBL14571460 | 0.87 | KMT2A (0.80) | KMT2AMEN1MAPTHSP90AA1ALDH1A1 | |
| SCHEMBL17643392 | 0.86 | MEN1 (0.74) | KMT2AMEN1MAPTHSP90AA1ALDH1A1 | |
| SCHEMBL17643018 | 0.85 | MEN1 (0.67) | KMT2AMEN1MAPTHSP90AA1ALDH1A1 | |
| SCHEMBL17643209 | 0.84 | MEN1 (0.80) | KMT2AMEN1MAPTHSP90AA1ALDH1A1 | |
| SCHEMBL17643398 | 0.84 | MEN1 (0.66) | KMT2AMEN1MAPTHSP90AA1ALDH1A1 | |
| SCHEMBL17643149 | 0.83 | KMT2A (0.74) | KMT2AMEN1MAPTHSP90AA1ALDH1A1 | |
| SCHEMBL17642981 | 0.83 | POLB (0.62) | KMT2AMEN1MAPTHSP90AA1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10544360-B2 | Materials for organic electroluminescent devices | MERCK PATENT GMBH (DE) | 2020-01-28 | — | — | US | disclosed |
| WO-2016045765-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2016-03-31 | — | — | WO | disclosed |