Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | AKT1 | P31749 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 3/20 | 0.48 |
| ▸ | ESR1 | P03372 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.45 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.45 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21658057 | 0.93 | MEN1 (0.64) | MEN1KMT2AMAPTHSP90AA1ALDH1A1 | |
| SCHEMBL17643400 | 0.92 | MEN1 (0.63) | MEN1KMT2AMAPTHSP90AA1ALDH1A1 | |
| SCHEMBL17642987 | 0.91 | MEN1 (0.65) | MEN1KMT2AMAPTHSP90AA1ALDH1A1 | |
| SCHEMBL17642973 | 0.91 | MEN1 (0.60) | MEN1KMT2AMAPTHSP90AA1ALDH1A1 | |
| SCHEMBL17643302 | 0.91 | MAPT (0.67) | MEN1KMT2AMAPTHSP90AA1ALDH1A1 | |
| SCHEMBL17642980 | 0.90 | MEN1 (0.65) | MEN1KMT2AMAPTHSP90AA1ALDH1A1 | |
| SCHEMBL17643144 | 0.90 | MEN1 (0.65) | MEN1KMT2AMAPTHSP90AA1ALDH1A1 | |
| SCHEMBL17643223 | 0.88 | MEN1 (0.68) | MEN1KMT2AMAPTHSP90AA1ALDH1A1 | |
| SCHEMBL17642983 | 0.87 | MEN1 (0.61) | MEN1KMT2AMAPTHSP90AA1ALDH1A1 | |
| SCHEMBL21658292 | 0.87 | MEN1 (0.57) | MEN1KMT2AMAPTHSP90AA1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3197982-B1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2020-05-06 | — | — | EP | disclosed |
| US-10544360-B2 | Materials for organic electroluminescent devices | MERCK PATENT GMBH (DE) | 2020-01-28 | — | — | US | disclosed |
| WO-2016045765-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2016-03-31 | — | — | WO | disclosed |