Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 6/20 | 0.63 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | ABL1 | P00519 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | PKM | P14618 | 1/20 | 0.56 |
| ▸ | IDE | P14735 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | HLCS | P50747 | 6/20 | 0.52 |
| ▸ | PLCD1 | P51178 | 1/20 | 0.46 |
| ▸ | HPSE | Q9Y251 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | CA9 | Q16790 | 1/20 | 0.45 |
| ▸ | F2 | P00734 | 1/20 | 0.45 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.45 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16625034 | 0.93 | TDP1 (0.69) | TDP1MEN1ABL1LMNAPKM | |
| SCHEMBL19627566 | 0.93 | TDP1 (0.69) | TDP1MEN1ABL1LMNAPKM | |
| SCHEMBL10029433 | 0.93 | TDP1 (0.69) | TDP1MEN1ABL1LMNAPKM | |
| SCHEMBL12424059 | 0.93 | TDP1 (0.69) | TDP1MEN1ABL1LMNAPKM | |
| SCHEMBL12010938 | 0.93 | TDP1 (0.69) | TDP1MEN1ABL1LMNAPKM | |
| SCHEMBL17170012 | 0.93 | TDP1 (0.69) | TDP1MEN1ABL1LMNAPKM | |
| SCHEMBL3431980 | 0.93 | TDP1 (0.69) | TDP1MEN1ABL1LMNAPKM | |
| SCHEMBL13065000 | 0.93 | TDP1 (0.69) | TDP1MEN1ABL1LMNAPKM | |
| SCHEMBL81912 | 0.93 | TDP1 (0.69) | TDP1MEN1ABL1LMNAPKM | |
| SCHEMBL10140187 | 0.91 | TDP1 (0.62) | TDP1MEN1ABL1LMNAPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3201235-A1 | ANTIBODIES TO TICAGRELOR AND METHODS OF USE | Medimmune Limited (GB) | 2017-08-09 | — | — | EP | disclosed |
| WO-2016050867-A1 | ANTIBODIES TO TICAGRELOR AND METHODS OF USE | MEDIMMUNE LIMITED (GB) | 2016-04-07 | — | — | WO | disclosed |