Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.47 |
| ▸ | NFKB2 | Q00653 | 3/20 | 0.47 |
| ▸ | RELA | Q04206 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 5/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.41 |
| ▸ | ACR | P10323 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17279032 | 1.00 | NPC1 (0.47) | NPC1LMNANFKB1NFKB2RELA | |
| SCHEMBL16547099 | 1.00 | NPC1 (0.47) | NPC1LMNANFKB1NFKB2RELA | |
| SCHEMBL24599297 | 0.97 | NPC1 (0.46) | NPC1LMNANFKB1NFKB2RELA | |
| SCHEMBL18405974 | 0.95 | HTT (0.40) | NPC1LMNANFKB1NFKB2RELA | |
| SCHEMBL18405919 | 0.95 | HTT (0.40) | NPC1LMNANFKB1NFKB2RELA | |
| SCHEMBL13072608 | 0.95 | HTT (0.40) | NPC1LMNANFKB1NFKB2RELA | |
| SCHEMBL26365062 | 0.93 | NPC1 (0.41) | NPC1LMNANFKB1NFKB2RELA | |
| SCHEMBL26365068 | 0.93 | NPC1 (0.41) | NPC1LMNANFKB1NFKB2RELA | |
| SCHEMBL26365052 | 0.93 | NPC1 (0.41) | NPC1LMNANFKB1NFKB2RELA | |
| SCHEMBL26365056 | 0.93 | NPC1 (0.41) | NPC1LMNANFKB1NFKB2RELA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3368285-B1 | METHOD OF MAKING OPTICAL ARTICLES HAVING GRADIENT LIGHT INFLUENCING PROPERTIES | TRANSITIONS OPTICAL INC (US) | 2026-04-15 | — | — | EP | disclosed |
| EP-3368927-B1 | OPTICAL ARTICLE WITH GRADIENT LIGHT INFLUENCING PROPERTIES AND METHOD OF MAKING THE SAME | TRANSITIONS OPTICAL INC (US) | 2024-10-16 | — | — | EP | disclosed |
| EP-3368926-B1 | A METHOD OF MAKING AN OPTICAL ARTICLE WITH AN INKJET PRINTING DEVICE | TRANSITIONS OPTICAL LTD (IE) | 2024-03-06 | — | — | EP | disclosed |
| US-11714220-B2 | Optical article with gradient light influencing properties and method of making the same | TRANSITIONS OPTICAL, INC. (US) | 2023-08-01 | — | — | US | disclosed |
| US-20220171110-A1 | Optical Articles and Method of Preparing the Same | TRANSITIONS OPTICAL, INC. | 2022-06-02 | — | — | US | disclosed |
| US-20220066081-A1 | Optical Article with Gradient Light Influencing Properties and Method of Making the Same | TRANSITIONS OPTICAL, INC. | 2022-03-03 | — | — | US | disclosed |
| US-11256014-B2 | Optical articles and method of preparing the same | TRANSITIONS OPTICAL, INC. (US) | 2022-02-22 | — | — | US | disclosed |
| US-11199653-B2 | Optical article with gradient light influencing properties and method of making the same | TRANSITIONS OPTICAL, INC. (US) | 2021-12-14 | — | — | US | disclosed |
| US-11036065-B2 | Method of making an optical article with an inkjet printing device | TRANSITIONS OPTICAL, LTD. (IE) | 2021-06-15 | — | — | US | disclosed |
| US-10619098-B2 | Ultraviolet light absorbers | TRANSITIONS OPTICAL, INC. (US) | 2020-04-14 | — | — | US | disclosed |
| US-20180299600-A1 | Optical Article with Gradient Light Influencing Properties and Method of Making the Same | TRANSITIONS OPTICAL, INC. | 2018-10-18 | — | — | US | disclosed |
| US-20180299702-A1 | Method of Making an Optical Article with an Inkjet Printing Device | TRANSITIONS OPTICAL, LTD. (IE) | 2018-10-18 | — | — | US | disclosed |
| US-20180299599-A1 | Optical Articles and Method of Preparing the Same | TRANSITIONS OPTICAL, INC. | 2018-10-18 | — | — | US | disclosed |
| US-20180290408-A1 | Method of Making Optical Articles Having Gradient Light Influencing Properties | TRANSITIONS OPTICAL, INC. | 2018-10-11 | — | — | US | disclosed |
| EP-3201292-B1 | ULTRAVIOLET LIGHT ABSORBERS | TRANSITIONS OPTICAL INC (US) | 2018-08-01 | — | — | EP | disclosed |
| US-20170275534-A1 | ULTRAVIOLET LIGHT ABSORBERS | TRANSITIONS OPTICAL, INC. | 2017-09-28 | — | — | US | disclosed |
| EP-3201292-A1 | ULTRAVIOLET LIGHT ABSORBERS | Transitions Optical, Inc. (US) | 2017-08-09 | — | — | EP | disclosed |
| WO-2016053662-A1 | ULTRAVIOLET LIGHT ABSORBERS | TRANSITIONS OPTICAL, INC. (US) | 2016-04-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10619098-B2 | Ultraviolet light absorbers | ERCC1, MCM4, ERCC4 | NPC1 1292/4885LMNA 498/4885NFKB1 2457/4885 |
| US-20170275534-A1 | ULTRAVIOLET LIGHT ABSORBERS | MCM4, ERCC1, ERCC4 | NPC1 939/4885LMNA 821/4885NFKB1 2330/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.