Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14899188 | 0.90 | GCKR (0.46) | GCKRGCK | |
| SCHEMBL23756 | 0.84 | GCK (0.56) | GCKRGCK | |
| SCHEMBL18932 | 0.84 | GCK (0.56) | GCKRGCK | |
| SCHEMBL12078969 | 0.84 | GCK (0.56) | GCKRGCK | |
| SCHEMBL12078852 | 0.84 | GCK (0.56) | GCKRGCK | |
| SCHEMBL12093399 | 0.84 | GCK (0.56) | GCKRGCK | |
| SCHEMBL17151 | 0.82 | GCKR (0.52) | GCKRGCK | |
| SCHEMBL14899167 | 0.77 | GCKR (0.59) | GCKRGCK | |
| SCHEMBL12089131 | 0.76 | GCK (0.55) | GCKRGCK | |
| SCHEMBL12089306 | 0.76 | GCK (0.55) | GCKRGCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012027261-A1 | SULFONYLPIPERAZINE DERIVATIVES THAT INTERACT WITH GLUCOKINASE REGULATORY PROTEIN FOR THE TREATMENT OF DIABETES | AMGEN INC. (US) | 2012-03-01 | — | — | WO | disclosed |