Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1671744 | 0.79 | HCRTR1 (1.00) | HCRTR1HCRTR2 | |
| SCHEMBL1671275 | 0.71 | HCRTR1 (1.00) | HCRTR1HCRTR2 | |
| SCHEMBL1673100 | 0.70 | HCRTR1 (1.00) | HCRTR1HCRTR2 | |
| SCHEMBL1671694 | 0.70 | HCRTR1 (1.00) | HCRTR1HCRTR2 | |
| SCHEMBL11920242 | 0.70 | HCRTR1 (0.79) | HCRTR1HCRTR2 | |
| SCHEMBL1671332 | 0.70 | HCRTR1 (1.00) | HCRTR1HCRTR2 | |
| SCHEMBL1671102 | 0.70 | HCRTR2 (1.00) | HCRTR1HCRTR2 | |
| SCHEMBL1671647 | 0.69 | HCRTR1 (1.00) | HCRTR1HCRTR2 | |
| SCHEMBL1671336 | 0.69 | HCRTR1 (1.00) | HCRTR1HCRTR2 | |
| SCHEMBL1670977 | 0.69 | HCRTR1 (1.00) | HCRTR1HCRTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3093291-B1 | DISUBSTITUTED OCTAHY - DROPYRROLO [3,4-C]PYRROLES AS OREXIN RECEPTOR MODULATORS | JANSSEN PHARMACEUTICA NV (BE) | 2019-05-08 | — | — | EP | disclosed |
| EP-2491038-B1 | DISUBSTITUTED OCTAHY - DROPYRROLO [3,4-C]PYRROLES AS OREXIN RECEPTOR MODULATORS | JANSSEN PHARMACEUTICA NV (BE) | 2016-04-06 | — | — | EP | disclosed |