⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1953883 | 0.69 | — | — | |
| SCHEMBL1953881 | 0.69 | — | — | |
| SCHEMBL17832847 | 0.69 | — | — | |
| SCHEMBL17770263 | 0.67 | — | — | |
| Hydrochloric Acid SCHEMBL22207609 | 0.67 | — | — | |
| SCHEMBL23374164 | 0.67 | — | — | |
| SCHEMBL14980667 | 0.67 | — | — | |
| Hydrochloric Acid SCHEMBL22207610 | 0.67 | CETP (0.43) | — | |
| Hydrochloric Acid SCHEMBL17824494 | 0.67 | — | — | |
| SCHEMBL18355395 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2763975-B1 | 3-PYRIDYL CARBOXAMIDE-CONTAINING SPLEEN TYROSINE KINASE (SYK) INHIBITORS | MERCK SHARP & DOHME (US) | 2016-04-06 | — | — | EP | disclosed |