2,4-Dichlorophenoxyacetic Acid

2,4-Dichlorophenoxyacetic Acid

SCHEMBL1765635

NN.O=C(O)COc1ccc(Cl)cc1Cl

nearest known ligand 0.93

Full drug profile on Sugi Atlas →

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 2/20 0.93
TSHR P16473 2/20 0.82
MAPT P10636 1/20 0.64
PTGDR2 Q9Y5Y4 5/20 0.60
CYP2C19 P33261 1/20 0.60
SMN1; SMN2 Q16637 2/20 0.59
RECQL P46063 1/20 0.59
HTT P42858 1/20 0.57
PTGDR Q13258 1/20 0.57
PPARD Q03181 1/20 0.57
GAA P10253 1/20 0.56
HPGD P15428 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
2,4-Dichlorophenoxyacetic Acid SCHEMBL31108925 0.96 TDP1 (1.00) TDP1TSHRMAPTPTGDR2CYP2C19
2,4-Dichlorophenoxyacetic Acid SCHEMBL27783 0.96 TDP1 (1.00) TDP1TSHRMAPTPTGDR2CYP2C19
2,4-Dichlorophenoxyacetic Acid SCHEMBL11716042 0.96 TDP1 (1.00) TDP1TSHRMAPTPTGDR2CYP2C19
2,4-Dichlorophenoxyacetic Acid SCHEMBL226803 0.96 TDP1 (1.00) TDP1TSHRMAPTPTGDR2CYP2C19
2,4-Dichlorophenoxyacetic Acid SCHEMBL28929149 0.95 TDP1 (0.90) TDP1TSHRMAPTPTGDR2CYP2C19
2,4-Dichlorophenoxyacetic Acid SCHEMBL17891942 0.95 TDP1 (0.96) TDP1TSHRMAPTPTGDR2CYP2C19
2,4-Dichlorophenoxyacetic Acid SCHEMBL13571538 0.95 TDP1 (0.96) TDP1TSHRMAPTPTGDR2CYP2C19
2,4-Dichlorophenoxyacetic Acid SCHEMBL7618485 0.95 TDP1 (0.96) TDP1TSHRMAPTPTGDR2CYP2C19
2,4-Dichlorophenoxyacetic Acid SCHEMBL4586671 0.95 TDP1 (0.96) TDP1TSHRMAPTPTGDR2CYP2C19
2,4-Dichlorophenoxyacetic Acid SCHEMBL9590404 0.95 TDP1 (0.96) TDP1TSHRMAPTPTGDR2CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110124503-A1 NOVEL HERBICIDE RESISTANCE GENES DOW AGROSCIENCES LLC (US) 2011-05-26 US disclosed
US-20110124502-A1 PEST CONTROL COMPOSITIONS AND METHODS WILMINGTON TRUST, NATIONAL ASSOCIATION, AS ADMINISTRATIVE AGENT 2011-05-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110124503-A1 NOVEL HERBICIDE RESISTANCE GENES ALDH7A1, AGXT, AADAC TDP1 2044/4885TSHR 3416/4885MAPT 4314/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.