Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 3/20 | 1.00 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | PDE9A | O76083 | 1/20 | 0.30 |
| ▸ | DUT | P33316 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | HTR6 | P50406 | 1/20 | 0.30 |
| ▸ | PARP1 | P09874 | 1/20 | 0.30 |
| ▸ | TACR1 | P25103 | 1/20 | 0.30 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.30 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL300529 | 1.00 | CNR2 (1.00) | CNR2MEN1KMT2APDE9ADUT | |
| SCHEMBL13745252 | 1.00 | CNR2 (1.00) | CNR2MEN1KMT2APDE9ADUT | |
| SCHEMBL257655 | 1.00 | CNR2 (1.00) | CNR2MEN1KMT2APDE9ADUT | |
| SCHEMBL176472 | 1.00 | CNR2 (1.00) | CNR2MEN1KMT2APDE9ADUT | |
| SCHEMBL176561 | 0.92 | CNR2 (0.85) | CNR2TBXA2RPTGDR | |
| SCHEMBL176431 | 0.91 | CNR2 (0.83) | CNR2DUTMAPK1PARP1TACR1 | |
| SCHEMBL13745207 | 0.91 | CNR2 (0.83) | CNR2DUTMAPK1PARP1TACR1 | |
| SCHEMBL13011098 | 0.90 | CNR2 (0.82) | CNR2DUTTACR1TBXA2RPTGDR | |
| SCHEMBL13867023 | 0.86 | CNR2 (0.75) | CNR2MEN1KMT2A | |
| SCHEMBL14267538 | 0.84 | CNR2 (0.72) | CNR2TBXA2RPTGDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1937259-B1 | HEXAHYDRO-CYCLOHEPTAPYRAZOLE CANNABINOID MODULATORS | JANSSEN PHARMACEUTICA NV (BE) | 2011-11-23 | — | — | EP | disclosed |