Zinc Ion

Zinc Ion

SCHEMBL1765831

NC(=S)[S-].NC(=S)[S-].[Fe].[Zn+2]

nearest known ligand 0.55

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 8/20 0.55
CA2 P00918 8/20 0.55
CA4 P22748 3/20 0.55
TSHR P16473 1/20 0.46
ATM Q13315 1/20 0.46
ATR Q13535 1/20 0.46
CA12 O43570 6/20 0.38
CA9 Q16790 6/20 0.38
ALDH1A1 P00352 4/20 0.38
HSD17B10 Q99714 4/20 0.38
HPGD P15428 3/20 0.38
ALOX15 P16050 2/20 0.38
MAPK1 P28482 2/20 0.38
TDP1 Q9NUW8 2/20 0.38
TP53 P04637 1/20 0.38
ALOX12 P18054 1/20 0.38
HIF1A Q16665 1/20 0.38
THRB P10828 2/20 0.33
CYP3A4 P08684 1/20 0.33
RECQL P46063 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Zinc Ion SCHEMBL59921 0.95
Zinc Ion SCHEMBL11215945 0.95 CA1 (0.60) CA1CA2CA4TSHRATM
Zinc Ion SCHEMBL30827139 0.95 CA1 (0.60) CA1CA2CA4TSHRATM
Zinc Ion SCHEMBL23500345 0.90 CA1 (0.55) CA1CA2CA4TSHRATM
Zinc Ion SCHEMBL28682973 0.90 CA1 (0.55) CA1CA2CA4TSHRATM
SCHEMBL7059931 0.90 CA1 (0.55) CA1CA2CA4TSHRATM
Zinc Ion SCHEMBL28323377 0.90 CA1 (0.55) CA1CA2CA4TSHRATM
Zinc Ion SCHEMBL28364625 0.90 CA1 (0.55) CA1CA2CA4TSHRATM
SCHEMBL29742330 0.89 CA1 (0.67) CA1CA2CA4TSHRATM
SCHEMBL451236 0.89

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8431511-B2 Hydroprocessing bulk catalyst and methods of making thereof CHEVRON U.S.A. INC. (US) 2013-04-30 US disclosed
US-8420565-B2 Hydroprocessing bulk catalyst and methods of making thereof CHEVRON U.S.A. INC. (US) 2013-04-16 US disclosed
US-8389433-B2 Hydroprocessing bulk catalyst and methods of making thereof CHEVRON U.S.A. (US) 2013-03-05 US disclosed
US-8372776-B2 Hydroprocessing bulk catalyst and methods of making thereof CHEVRON U.S.A. INC. (US) 2013-02-12 US disclosed
US-20110124493-A1 Hydroprocessing Bulk Catalyst and Methods of Making Thereof CHEVRON U.S.A. INC. 2011-05-26 US disclosed
US-20110124496-A1 Hydroprocessing Bulk Catalyst and Methods of Making Thereof CHEVRON U.S.A. INC. 2011-05-26 US disclosed
US-20110124494-A1 Hydroprocessing Bulk Catalyst and Methods of Making Thereof CHEVRON U.S.A. INC. 2011-05-26 US disclosed
US-20110124498-A1 Hydroprocessing Bulk Catalyst and Methods of Making Thereof CHEVRON U.S.A. INC. 2011-05-26 US disclosed