Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 5/20 | 0.62 |
| ▸ | PPARD | Q03181 | 5/20 | 0.62 |
| ▸ | PPARG | P37231 | 4/20 | 0.62 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | KCNJ6 | P48051 | 1/20 | 0.39 |
| ▸ | KCNJ5 | P48544 | 1/20 | 0.39 |
| ▸ | KCNJ3 | P48549 | 1/20 | 0.39 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.38 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1765936 | 0.94 | PPARD (0.68) | PPARAPPARDPPARGTDP1TSHR | |
| SCHEMBL12732439 | 0.93 | PPARA (0.54) | PPARAPPARDPPARGTDP1TSHR | |
| SCHEMBL24742416 | 0.90 | PPARA (0.50) | PPARAPPARDPPARGTDP1TSHR | |
| SCHEMBL30004652 | 0.90 | PPARA (0.50) | PPARAPPARDPPARGTDP1TSHR | |
| SCHEMBL2467711 | 0.89 | PPARG (0.56) | PPARAPPARDPPARGTDP1TSHR | |
| SCHEMBL4754218 | 0.88 | PPARA (0.49) | PPARAPPARDPPARGTSHRSMN1; SMN2 | |
| SCHEMBL2460899 | 0.87 | PPARD (0.59) | PPARAPPARDPPARGPTGDR2LPAR2 | |
| SCHEMBL1765978 | 0.87 | PPARA (0.61) | PPARAPPARDPPARGTSHRSMN1; SMN2 | |
| SCHEMBL4754216 | 0.86 | PPARA (0.48) | PPARAPPARDPPARGTSHRSMN1; SMN2 | |
| SCHEMBL12732396 | 0.86 | PPARG (0.57) | PPARAPPARDPPARGTSHRSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190255022-A1 | WOUND-HEALING AGENT | NIPPON CHEMIPHAR CO., LTD. (JP) | 2019-08-22 | — | — | US | claimed |
| EP-3456327-A1 | WOUND-HEALING AGENT | Nippon Chemiphar Co., Ltd. (JP) | 2019-03-20 | — | — | EP | claimed |
| US-7652045-B2 | e.g. [[7-Allyl-3-[2-[2-(2,4-dichlorophenyl)-5-isopropyl-4-oxazolyl]ethyl]-1,2-benzisoxazol-6-yl]oxy]acetic acid; with vehicles (lactose, D-mannitol, glucose), disintegrators (starch or carboxymethylcellulose calcium ), binders (hydroxypropylcellulose) and lubricants (magnesium stearate or talc) | NIPPON CHEMIPHAR, CO., LTD. (JP) | 2010-01-26 | — | — | US | claimed |
| US-20190255022-A1 | WOUND-HEALING AGENT | NIPPON CHEMIPHAR CO., LTD. (JP) | 2019-08-22 | — | — | US | disclosed |
| EP-3456327-A1 | WOUND-HEALING AGENT | Nippon Chemiphar Co., Ltd. (JP) | 2019-03-20 | — | — | EP | disclosed |
| EP-2464349-A2 | USE OF PPAR DELTA LIGANDS FOR THE TREATMENT OR PREVENTION OF INFLAMMATION OR ENERGY METABOLISM/PRODUCTION RELATED DISEASES | Cerenis Therapeutics S.A. (FR) | 2012-06-20 | — | — | EP | disclosed |
| EP-1424330-B1 | ACTIVATOR FOR PEROXISOME PROLIFERATOR-RESPONSIVE RECEPTOR DELTA | NIPPON CHEMIPHAR CO (JP) | 2011-09-28 | — | — | EP | disclosed |
| WO-2011020001-A9 | USE OF PPAR DELTA LIGANDS FOR THE TREATMENT OR PREVENTION OF INFLAMMATION OR ENERGY METABOLISM/PRODUCTION RELATED DISEASES | CERENIS THERAPEUTICS S.A. (FR) | 2011-05-26 | — | — | WO | disclosed |
| WO-2011020001-A2 | USE OF PPAR DELTA LIGANDS FOR THE TREATMENT OR PREVENTION OF INFLAMMATION OR ENERGY METABOLISM/PRODUCTION RELATED DISEASES | CERENIS THERAPEUTICS S.A. (FR) | 2011-02-17 | — | — | WO | disclosed |
| US-7652045-B2 | e.g. [[7-Allyl-3-[2-[2-(2,4-dichlorophenyl)-5-isopropyl-4-oxazolyl]ethyl]-1,2-benzisoxazol-6-yl]oxy]acetic acid; with vehicles (lactose, D-mannitol, glucose), disintegrators (starch or carboxymethylcellulose calcium ), binders (hydroxypropylcellulose) and lubricants (magnesium stearate or talc) | NIPPON CHEMIPHAR, CO., LTD. (JP) | 2010-01-26 | — | — | US | disclosed |
| US-7648999-B2 | Activator for peroxisome proliferator-activated receptor δ | NIPPON CHEMIPHAR CO., LTD. (JP) | 2010-01-19 | — | — | US | disclosed |
| WO-2008154023-A1 | NOVEL USES OF PPAR DELTA AGONISTS | CERENIS THERAPEUTICS S.A. (FR) | 2008-12-18 | — | — | WO | disclosed |
| US-20080009525-A1 | Activator of peroxisome proliferator-activated receptor delta | SAKUMA SHOGO | 2008-01-10 | — | — | US | disclosed |
| US-20080009631-A1 | Activator for peroxisome proliferator-activated receptor delta | SAKUMA SHOGO | 2008-01-10 | — | — | US | disclosed |
| US-7265137-B2 | Activator of peroxisome proliferator-activated re-ceptor δ | NIPPON CHEMIPHAR CO., LTD. (JP) | 2007-09-04 | — | — | US | disclosed |
| US-20050054674-A1 | Activator of peroxisome proliferator-activated receptor | NIPPON CHEMIPHAR CO., LTD. (JP) | 2005-03-10 | — | — | US | disclosed |
| EP-1424330-A1 | ACTIVATOR FOR PEROXISOME PROLIFERATOR-RESPONSIVE RECEPTOR DELTA | NIPPON CHEMIPHAR CO., LTD. (JP) | 2004-06-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080009525-A1 | Activator of peroxisome proliferator-activated receptor delta | PPARG, PPARD, PPARA | PPARA 3/4885PPARD 2/4885PPARG 1/4885 |
| US-20190255022-A1 | WOUND-HEALING AGENT | PPARG, PPARA, PPARD | PPARA 2/4885PPARD 3/4885PPARG 1/4885 |
| US-20080009631-A1 | Activator for peroxisome proliferator-activated receptor delta | PPARG, PPARD, PPARA | PPARA 3/4885PPARD 2/4885PPARG 1/4885 |
| US-20050054674-A1 | Activator of peroxisome proliferator-activated receptor | PPARG, PPARD, PPARA | PPARA 3/4885PPARD 2/4885PPARG 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.