Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 9/20 | 0.45 |
| ▸ | PPARD | Q03181 | 8/20 | 0.45 |
| ▸ | PPARG | P37231 | 7/20 | 0.45 |
| ▸ | S1PR3 | Q99500 | 8/20 | 0.34 |
| ▸ | S1PR5 | Q9H228 | 8/20 | 0.34 |
| ▸ | S1PR1 | P21453 | 7/20 | 0.34 |
| ▸ | SHMT1 | P34896 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.31 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
| ▸ | HTR2C | P28335 | 1/20 | 0.31 |
| ▸ | HTR2B | P41595 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2466184 | 0.92 | PPARD (0.52) | PPARAPPARDPPARG | |
| SCHEMBL20815372 | 0.92 | PPARD (0.47) | PPARAPPARDPPARGS1PR3S1PR5 | |
| SCHEMBL24742470 | 0.89 | PPARD (0.45) | PPARAPPARDPPARGS1PR3S1PR5 | |
| SCHEMBL30003542 | 0.89 | PPARD (0.45) | PPARAPPARDPPARGS1PR3S1PR5 | |
| SCHEMBL12732406 | 0.89 | PPARD (0.45) | PPARAPPARDPPARGS1PR3S1PR5 | |
| SCHEMBL2460886 | 0.88 | PPARA (0.43) | PPARAPPARDPPARGS1PR3S1PR5 | |
| SCHEMBL12732399 | 0.88 | PPARG (0.49) | PPARAPPARDPPARGS1PR3S1PR5 | |
| SCHEMBL2463893 | 0.85 | PPARD (0.60) | PPARAPPARDPPARGTSHRNPC1 | |
| SCHEMBL2460899 | 0.85 | PPARD (0.59) | PPARAPPARDPPARGMAPT | |
| SCHEMBL2463427 | 0.84 | PPARG (0.46) | PPARAPPARDPPARGS1PR3S1PR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011020001-A9 | USE OF PPAR DELTA LIGANDS FOR THE TREATMENT OR PREVENTION OF INFLAMMATION OR ENERGY METABOLISM/PRODUCTION RELATED DISEASES | CERENIS THERAPEUTICS S.A. (FR) | 2011-05-26 | — | — | WO | disclosed |